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52840-06-9

52840-06-9 Structure

52840-06-9 Structure
IdentificationBack Directory
[Name]

Lithocholic-2,2,3,4,4-d5 Acid
[CAS]

52840-06-9
[Synonyms]

Lithocholic-2,2,3,4,4-d5 Acid
[Molecular Formula]

C24H35O3D5
[MOL File]

52840-06-9.mol
[Molecular Weight]

381.603
Hazard InformationBack Directory
[Uses]

Lithocholic acid-d5 is deuterium labeled Lithocholic acid.
[References]

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Jenkins, D.J., et al., Effect on blood lipids of very high intakes of fiber in diets low in saturated fat and cholesterol. N Engl J Med, 1993. 329(1): p. 21-6. DOI:10.1056/NEJM199307013290104
[3] Yang R, et al. Metabolomic analysis of cholestatic liver damage in mice. Food Chem Toxicol. 2018 Jul 14;120:253-260. DOI:10.1016/j.fct.2018.07.022
[4] Goldberg, A.A., et al., Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells. Oncotarget, 2011. 2(10): p. 761-82. DOI:10.18632/oncotarget.338
[5] Matsubara, T., et al., TGF-beta-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury. J Lipid Res, 2012. 53(12): p. 2698-707. DOI:10.1194/jlr.M031773
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