| Identification | Back Directory | [Name]
GENTISEIN | [CAS]
529-49-7 | [Synonyms]
NSC329491
NSC-329491
NSC 329491
Gentisein(NSC 329491)
1,3,7-trihydroxyxanthen-9-one
1,3,7-Trihydroxy-9H-xanthen-9-one
9H-Xanthen-9-one,1,3,7-trihydroxy- | [Molecular Formula]
C13H8O5 | [MDL Number]
MFCD00210571 | [MOL File]
529-49-7.mol | [Molecular Weight]
244.2 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml,Ethanol: 20 mg/ml | [form ]
A solid | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Gentisein (NSC 329491), the major metabolite of Mangiferin, shows the most potent serotonin uptake inhibition with an IC50 value of 4.7 μM[1][2]. | [Definition]
ChEBI: A member of the class of xanthones that is 9H-xanthen-9-one substituted by hydroxy groups at positions 1, 3 and 7. | [storage]
-20°C | [References]
[1] Wang H, et al. Identification and determination of four metabolites of mangiferin in rat urine. J Pharm Biomed Anal. 2007;45(5):793-798. DOI:10.1016/j.jpba.2007.07.019
[2] Tzankova, Virginia et al. (2010). Inhibition of 5-HT uptake by some constituents of Hypericum annulatum in rat brain in vitro. Pharmacologyonline. 2. |
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