ChemicalBook--->CAS DataBase List--->52946-22-2

52946-22-2

52946-22-2 Structure

52946-22-2 Structure
IdentificationBack Directory
[Name]

ACETOXYCHAVICOL ACETATE, D/L-1''-
[CAS]

52946-22-2
[Synonyms]

Galangal acetate
1'-Acetoxychavicol acetate
DL-1''-ACETOXYCAVICOL ACETATE
D/L-1''-ACETOXCHAVICOL ACETATE
D,L-1'-ACETOXYCHAVICOL ACETATE
AcetoXychvicol acetate, D/L-1''-
ACETOXYCHAVICOL ACETATE, D/L-1''-
(1S)-1-[4-(acetyloxy)phenyl]prop-2-en-1-yl acetate
(S)-4-(Acetyloxy)-alpha-ethenylbenzenemethanol acetate
[Molecular Formula]

C13H14O4
[MDL Number]

MFCD01632488
[MOL File]

52946-22-2.mol
[Molecular Weight]

234.25
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 14 mg/mL,DMSO: 20 mg/mL,Ethanol: 20 mg/mL,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL
[Major Application]

food and beverages
[Cosmetics Ingredients Functions]

ANTIMICROBIAL
ANTI-SEBUM
[InChI]

1S/C13H14O4/c1-4-13(17-10(3)15)11-5-7-12(8-6-11)16-9(2)14/h4-8,13H,1H2,2-3H3/t13-/m0/s1
[InChIKey]

JAMQIUWGGBSIKZ-ZDUSSCGKSA-N
[SMILES]

O([C@H](c1ccc(cc1)OC(=O)C)C=C)C(=O)C
[LogP]

1.900 (est)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H335-H319
[Precautionary statements ]

P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Description]

D,L-1′-Acetoxychavicol acetate is a natural compound first isolated from the rhizomes of ginger-like plants. It has a wide array of cellular effects that may be largely explained by its ability to inhibit exportin 1 and prevent the export of proteins from the nucleus. In this way, D,L-1′-acetoxychavicol acetate reduces several intracellular signaling pathways, including NF-κB, impacting inflammation, cancer, viral replication, and other processes.
[Uses]

Galangal acetate is a wasabi-like spicy compound[1].
[Definition]

ChEBI: An acetate ester that is chavicol acetate substituted by an acetoxy group at position 1'.
[storage]

Store at -20°C
[References]

[1] Lin LY, et al. Integrated Process for Production of Galangal Acetate, the "Wasabi-Like" Spicy Compound, and Analysis of Essential Oils of Rhizoma Alpinia officinarum (Hance) Farw. J Food Sci. 2016 Jun;81(6):H1565-75. DOI:10.1111/1750-3841.13326
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