| Identification | Back Directory | [Name]
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID | [CAS]
53005-05-3 | [Synonyms]
4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid
4,4'-Bis(isothiocyanato)stilbene-2,2'-bissulfonic acid
4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid
2,2'-(1,2-Ethenediyl)bis(5-isothiocyanatobenzenesulfonic acid)
Benzenesulfonic acid,2,2'-(1,2-ethenediyl)bis[5-isothiocyanato-
4,4′-Diisotbiocyano-2,2′-stilbenedisulfnic Acid Disodium Salt | [Molecular Formula]
C16H10N2O6S4 | [MDL Number]
MFCD00065493 | [MOL File]
53005-05-3.mol | [Molecular Weight]
454.52 |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow Crystalline Solid | [Uses]
Stilbene disulfonates have been employed to inhibit anion transport in a large number of mammalian cell types (GABA, Cl-). Some stilbene disulfonates can bind specifically to proteins that are not anion transporters. DIDS reacts with CD4 glycoprot | [Uses]
Ion channel inhibitor; especially of anion transport. | [Definition]
ChEBI: 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid is an arenesulfonic acid. | [General Description]
Binds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl– uptake (IC50 = 150 nM) in neuroblastoma cells. Has anti-ulcerous properties. | [Biochem/physiol Actions]
Primary TargetCl- uptake |
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