| Identification | Back Directory | [Name]
6-METHOXY-2-BENZOXAZOLINONE | [CAS]
532-91-2 | [Synonyms]
mboa
Coixol
6-Mboa
6-Methoxybenzoxazolinone
6-Methoxy-2-benzoxazoline
6-Methoxy benzoxazol-2-one
6-methoxy-2-benzoxazolinon
6-METHOXY-2-BENZOXAZOLININE
6-METHOXY-2-BENZOXAZOLINONE
6-methoxy-2(3h)-benzoxazolon
6-methoxy-2(3h)-benzoxazolone
6-Methoxy-3H-benzoxazol-2-one
2-Benzoxazolinone, 6-methoxy-
6-Methoxybenzoxazol-2(3H)-one
2(3H)-Benzoxazolone, 6-methoxy-
6-Methoxy-2-benzoxazolinone,98+%
6-methoxy-3H-1,3-benzoxazol-2-one
6-METHOXYBENZO[D]OXAZOL-2(3H)-ONE
6-Methoxy-1,3-benzoxazol-2(3H)-one
6-Methoxy-2(3H)-benzoxazolone, 98+%
Coixol (6-Methoxy-2-benzoxazolinone
6-Methoxy-2,3-dihydrobenzoxazole-2-one
JRH-04701, 6-Methoxybenzo[d]oxazol-2(3H)-one, 97% | [Molecular Formula]
C8H7NO3 | [MDL Number]
MFCD00051726 | [MOL File]
532-91-2.mol | [Molecular Weight]
165.15 |
| Chemical Properties | Back Directory | [Melting point ]
151-156 °C(lit.)
| [Boiling point ]
292.97°C (rough estimate) | [density ]
1.3450 (rough estimate) | [refractive index ]
1.5468 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
Acetone, Dichloromethane, Methanol, Tetrahydrofuran | [form ]
Solid | [pka]
8.73±0.70(Predicted) | [color ]
light tan
| [BRN ]
141041 |
| Hazard Information | Back Directory | [Chemical Properties]
It is a white powder, soluble in organic solvents such as methanol, ethanol, and DMSO. It comes from the rhizomes of Imperata cylindrica, the rhizomes of Phragmites australis, and the seeds and roots of Coix lachryma-jobi. | [Uses]
6-Methoxybenzoxazolinone is an intermdiate in the synthesis of DIMBOA-4-O-β-D-glucuronide which is a metabolite of DIMBOA which acts as an antifungal and antialgal agent in crops. The benzoxazinone group within the structure allows for these effects. | [Definition]
ChEBI: Coixol is a benzoxazole. | [Synthesis Reference(s)]
Synthetic Communications, 23, p. 343, 1993 DOI: 10.1080/00397919308009786 | [General Description]
6-Methoxy-2-benzoxazolinone (MBOA) is obtained by reacting 2-amino-5-methoxyphenol hydrochloride with urea. MOBA is a naturally occurring auxin-inhibiting substance present in maize shoots. | [in vivo]
| Animal Model: | 9–12 weeks, Sprague Dawley (SD) male rats[3] | | Dosage: | 25, 50 mg/kg | | Administration: | P.o. | | Result: | Decreased the blood glucose levels significantly, improved glucose tolerance. |
| [storage]
Store at 4°C |
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