| Identification | Back Directory | [Name]
EZETIMIBE HYDROXY GLUCURONIDE | [CAS]
536709-33-8 | [Synonyms]
SCH 488128
EZETIMIBE HYDROXY GLUCURONIDE
Ezetimibe Hydroxy -D-Glucuronide
Ezetimibe Hydroxy b-D-Glucuronide
(2S,3S,4S,5R,6R)-6-((S)-1-(4-Fluorophenyl)-3-((2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4
(1S)-1-(4-Fluorophenyl)-3-[(2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxo-3-azetidinyl]propyl -D-Glucopyranosiduronic Acid
(1S)-1-(4-Fluorophenyl)-3-[(2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxo-3-azetidinyl]propyl b-D-Glucopyranosiduronic Acid
(1S)-1-(4-Fluorophenyl)-3-[(2S,3R)-1-(4-fluorophenyl)-2-(4-hydroxyphenyl)-4-oxo-3-azetidinyl]propyl beta-D-glucopyranosiduronic acid | [Molecular Formula]
C30H29F2NO9 | [MDL Number]
MFCD08063722 | [MOL File]
536709-33-8.mol | [Molecular Weight]
585.55 |
| Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
127-129°C | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Off-White |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
A metabolite of Ezetimibe. Antilipemic | [Description]
Ezetimibe hydroxy glucuronide is a minor phase II glucuronide metabolite of ezetimibe . | [References]
[1] TAKAKO FURUKAWA. Quantitative Prediction of Intestinal Glucuronidation of Drugs in Rats Using In Vitro Metabolic Clearance Data[J]. Drug Metabolism and Pharmacokinetics, 2012, 27 2: Pages 171-180. DOI: 10.2133/dmpk.dmpk-11-rg-088 |
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