| Identification | Back Directory | [Name]
8-AZIDOADENOSINE 5'-TRIPHOSPHATE, SODIUM SALT | [CAS]
53696-59-6 | [Synonyms]
8-N3-ATP SODIUM SALT 8-azidoadenosine5’-triphosphate 8-azido-ATP - 10mM aqueous solution 8-azidoadenosine5’-triphosphatesodium 8-Azido-D-adenosine5'-triphosphatesodiumsalt 8-AZIDOADENOSINE 5'-TRIPHOSPHATE, SODIUM SALT 8-AZIDOADENOSINE-5'-O-TRIPHOSPHATE SODIUM SALT Adenosine 5'-(tetrahydrogen triphosphate), 8-azido- 8-azidoadenosine-5’-o-triphosphate(8-n3-atp),sodiumsalt 8-AZIDOADENOSINE 5'-TRIPHOSPHATE, SODIUM SALT USP/EP/BP 8-Azidoadenosine 5'-triphosphate sodium salt - 10mM aqueous solution | [Molecular Formula]
C10H15N8O13P3 | [MDL Number]
MFCD02091657 | [MOL File]
53696-59-6.mol | [Molecular Weight]
548.19 |
| Hazard Information | Back Directory | [Uses]
8-Azido-ATP, a photoreactable nucleotide analog, is useful for the identification of proteins, such as DNA-dependent RNA polymerase[1]. 8-Azido-ATP is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [References]
[1] S Valenzuela, et al. Photoaffinity labeling of rotavirus VP1 with 8-azido-ATP: identification of the viral RNA polymerase. J Virol. 1991 Jul;65(7):3964-7. DOI:10.1128/JVI.65.7.3964-3967.1991 [2] K Tanabe, et al. Direct photoaffinity labeling of the Kir6.2 subunit of the ATP-sensitive K+ channel by 8-azido-ATP. J Biol Chem. 1999 Feb 12;274(7):3931-3. DOI:10.1074/jbc.274.7.3931 |
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