| Identification | Back Directory | [Name]
rociverine | [CAS]
53716-44-2 | [Synonyms]
rociverine
53716-44-2
Rociverinum
Rociverine (base and/or unspecified salts)
1-Hydroxy-[1,1'-bi(cyclohexane)]-2-carboxylic acid 2-(diethylamino)-1-methylethyl ester
[1,1'-Bicyclohexyl]-2-carboxylic acid, 1-hydroxy-, 2-(diethylamino)-1-methylethyl ester, (1R,2R)-rel- | [EINECS(EC#)]
258-711-9 | [Molecular Formula]
C20H37NO3 | [MDL Number]
MFCD00870857 | [MOL File]
53716-44-2.mol | [Molecular Weight]
339.51 |
| Hazard Information | Back Directory | [Uses]
Rociverine is an anticholinergic compound with smooth muscle relaxant activity. Rociverine showed different binding modes in five cloned muscarinic receptors. The cis stereoisomer of Rociverine showed a higher affinity change compared to the trans stereoisomer. The (1R,2R) configuration of Rociverine showed significantly higher affinity, even up to 240 times. The (1S,2S) configuration of Rociverine is very important for binding selectivity[1]. | [References]
[1] Stereoselective inhibition of muscarinic receptor subtypes by the eight stereoisomers related to rociverine |
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PT CHEM GROUP LIMITED
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