| Identification | Back Directory | [Name]
Trimazosin hydrochloride | [CAS]
53746-46-6 | [Synonyms]
Trimazosin HCl
Unii-827T79Ile7
Trimazosin hydrochloride
Trimazosin hydrochlorid-1-wasser
Trimazosin hydrochloride monohydrate
Trimazosin monohydrochloride monohydrate
4-(4-AMino-6,7,8-triMethoxy-2-quinazolinyl)-1-piperazinecarboxylic Acid 2-Hydroxy-2-Methylpropyl Ester Hydrochloride | [Molecular Formula]
C20H29N5O6.ClH.H2O | [MDL Number]
MFCD00941413 | [MOL File]
53746-46-6.mol | [Molecular Weight]
489.954 |
| Chemical Properties | Back Directory | [Melting point ]
166-169° (dec) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Slightly) | [form ]
Solid | [color ]
Off-White to Light Beige |
| Hazard Information | Back Directory | [Description]
Trimazosin hydrochloride is a selective
αl-adrenergic antagonist related to
prazosin, bunazosin, and terazosin. It is reported to be longer acting than
prazosin, without first dose hypotensive effects. | [Originator]
Pfizer (USA) | [Uses]
Trimazosin is useful in therapy as potent antihypertensive agents. | [Brand name]
SUPRES | [IC 50]
α1-adrenergic receptor |
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