| Identification | Back Directory | [Name]
(+)-(3AR,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-[(1E,3R)-3-HYDROXY-4-(3-TRIFLUOROMETHYL)PHENOXY-1-BUTENYL]-2H-CYCLOPENTA[B]FURAN-2-ONE | [CAS]
53872-60-9 | [Synonyms]
TRT
EST2
TCS1
TP-2
TV-DI
HYDRIDE-T
TP-2 (TV-EDI)
ravoprost Epoxide
Travoprost Epoxide
Travoprost Impurity 13
Curved prostate impurity
Fluprostenone Lactone Diol
TP-2 (TV-EDI) (Travoprost)
(+)-FLUPROSTENOL LACTONE DIOL
Anti-TERT antibody produced in goat
Anti-Telomerase antibody produced in rabbit
(3AR,4R,5R,6aS)-5-Hydroxy-4-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)-phenoxy)but-1-en-1-yl)hexa
(3AR,4R,5R,6aS)-5-Hydroxy-4-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)-phenoxy)but-1-en-1-yl)hexahyd
(3aR,4R,5R,6aS)-5-Hydroxy-4-((R,E)-3-hydroxy-4-(3-(trifluoroMethyl)phenoxy)but-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-one
(+)-(3AR,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-[(1E,3R)-3-HYDROXY-4-(3-TRIFLUOROMETHYL)PHENOXY-1-BUTENYL]-2H-CYCLOPENTA[B]FURAN-2-ONE
(+)-(3AR,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-[(1E,3R)-3-HYDROXY-4-(3-TRIFLUOROMETHYL)PHENOXY-1-BUTENYL]-2H-CYCLOPENTA[B]FURAN-2-ONE
(3aR,4R,5R,6aS)-5-hydroxy-4-[(3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one
2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-, (3aR,4R,5R,6aS)-
(+)-(3aR,4R,5r,6aS)-Hexahydro-5-hydroxy-4-[(1E,3R)-3-hydroxy-4-(3-trifluoromethyl)phenoxy-1-butenyl]-2H-cyclopenta[b]furan-2-one(N-3)
53872-60-9 (+)-(3AR,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-[(1E,3R)-3-HYDROXY-4-(3-TRIFLUOROMETHYL)PHENOXY-1-BUTENYL]-2H-CYCLOPENTA[B]FURAN-2-ONE
(3aR,?4R,?5R,?6aS)?-Hexahydro-?5-?hydroxy-?4-?[(1E,?3R)?-?3-?hydroxy-?4-?[3-?(trifluoromethyl)?phenoxy]?-?1-?buten-?1-?yl]?-?2H-?cyclopenta[b]?furan-?2-?one | [Molecular Formula]
C18H19F3O5 | [MDL Number]
MFCD22422511 | [MOL File]
53872-60-9.mol | [Molecular Weight]
372.34 |
| Chemical Properties | Back Directory | [Boiling point ]
520.6±50.0 °C(Predicted) | [density ]
1.433±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMF: 25 mg/ml; DMF:PBS (pH 7.2) (1:10): 100 μg/ml; DMSO: 17 mg/ml; Ethanol: 20 mg/ml | [form ]
A crystalline solid | [pka]
13.34±0.20(Predicted) | [biological source]
rabbit |
| Hazard Information | Back Directory | [Uses]
(3aR,?4R,?5R,?6aS)?-Hexahydro-?5-?hydroxy-?4-?[(1E,?3R)?-?3-?hydroxy-?4-?[3-?(trifluoromethyl)?phenoxy]?-?1-?buten-?1-?yl]?-?2H-?cyclopenta[b]?furan-?2-?one is involved in the preparation of prostaglandin derivatives. | [Biological Activity]
TERT (telomerase reverse transcriptase) catalyzes the de novo synthesis of telomere and results in cellular immortalization to maintain chromosomal stability. Mutations in TERT causes different types of malignancies such as gliomasgastric cancerand anaplastic thyroid cancer. ThereforeTERT serves as an early prognostic biomarker. |
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