ChemicalBook--->CAS DataBase List--->53934-76-2

53934-76-2

53934-76-2 Structure

53934-76-2 Structure
IdentificationBack Directory
[Name]

(2-OXOPYRROLIDIN-1-YL)ACETIC ACID
[CAS]

53934-76-2
[Synonyms]

Piracetam Impuirty D
Piracetam Impurity 1
Piracetam EP Impurity D
2-Pyrrolidinon-1-ylacetic acid
2-(2-oxopyrrolidin-1-yl)acetate
1-Pyrrolidineacetic acid, 2-oxo-
2-(2-oxo-1-pyrrolidinyl)acetic acid
(2-Oxo-1-pyrrolidinyl)aceticacid,97%
2-(2-ketopyrrolidin-1-yl)acetic acid
2-(2-oxopyrrolidin-1-yl)ethanoic acid
Piracetam Impurity 4(Piracetam EP Impurity D)
(2-oxopyrrolidin-1-yl)acetic acid(SALTDATA: FREE)
2-Oxo-1-pyrrolidineacetic acid (Piracetam Impurity)
(2-Oxo-1-pyrrolidin)-acetic acidQ: What is (2-Oxo-1-pyrrolidin)-acetic acid Q: What is the CAS Number of (2-Oxo-1-pyrrolidin)-acetic acid Q: What is the storage condition of (2-Oxo-1-pyrrolidin)-acetic acid Q: What are the applications of (2-Oxo-1-pyrrolidin)-acetic acid
[Molecular Formula]

C6H9NO3
[MDL Number]

MFCD00962836
[MOL File]

53934-76-2.mol
[Molecular Weight]

143.14
Chemical PropertiesBack Directory
[Melting point ]

143℃ (benzene )
[Boiling point ]

379.1±25.0 °C(Predicted)
[density ]

1.319±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

Chloroform (Sparingly), Ethyl Acetate (Slightly, Heated), Methanol (Slightly)
[form ]

Solid
[pka]

3.75±0.10(Predicted)
[Appearance]

Off-white to light yellow Solid
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard InformationBack Directory
[Uses]

(2-Oxopyrrolidin-1-yl)acetic acid is a reagent in the preparation of pyrazolopyridines as PDE4B inhibitors.
[Synthesis]

1-Pyrrolidineacetic acid, 2-oxo-, phenylmethyl ester

143023-95-4

(2-OXOPYRROLIDIN-1-YL)ACETIC ACID

53934-76-2

Benzyl (2-oxopyrrolidin-1-yl) acetate (233 mg, 1.0 mmol) was dissolved in methanol (5 mL) at 23 °C and 10 wt% Pd/C catalyst (100 mg) was added. The reaction mixture was deoxygenated using a vacuum pump and subsequently reacted under hydrogen atmosphere (using a hydrogen balloon).After 3 h, the reaction mixture was filtered through a diatomaceous earth pad and the diatomaceous earth pad was washed with methanol (100 mL). The combined filtrates were concentrated under reduced pressure to afford (2-oxopyrrolidin-1-yl)acetic acid (143 mg, 100% yield).

[References]

[1] Patent: US2006/211603, 2006, A1. Location in patent: Page/Page column 76
Spectrum DetailBack Directory
[Spectrum Detail]

(2-OXOPYRROLIDIN-1-YL)ACETIC ACID(53934-76-2)1HNMR
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