| Identification | Back Directory | [Name]
(2-OXOPYRROLIDIN-1-YL)ACETIC ACID | [CAS]
53934-76-2 | [Synonyms]
Piracetam Impuirty D
Piracetam Impurity 1
Piracetam EP Impurity D
2-Pyrrolidinon-1-ylacetic acid
2-(2-oxopyrrolidin-1-yl)acetate
1-Pyrrolidineacetic acid, 2-oxo-
2-(2-oxo-1-pyrrolidinyl)acetic acid
(2-Oxo-1-pyrrolidinyl)aceticacid,97%
2-(2-ketopyrrolidin-1-yl)acetic acid
2-(2-oxopyrrolidin-1-yl)ethanoic acid
Piracetam Impurity 4(Piracetam EP Impurity D)
(2-oxopyrrolidin-1-yl)acetic acid(SALTDATA: FREE)
2-Oxo-1-pyrrolidineacetic acid (Piracetam Impurity)
(2-Oxo-1-pyrrolidin)-acetic acidQ: What is
(2-Oxo-1-pyrrolidin)-acetic acid Q: What is the CAS Number of
(2-Oxo-1-pyrrolidin)-acetic acid Q: What is the storage condition of
(2-Oxo-1-pyrrolidin)-acetic acid Q: What are the applications of
(2-Oxo-1-pyrrolidin)-acetic acid | [Molecular Formula]
C6H9NO3 | [MDL Number]
MFCD00962836 | [MOL File]
53934-76-2.mol | [Molecular Weight]
143.14 |
| Chemical Properties | Back Directory | [Melting point ]
143℃ (benzene ) | [Boiling point ]
379.1±25.0 °C(Predicted) | [density ]
1.319±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Sparingly), Ethyl Acetate (Slightly, Heated), Methanol (Slightly) | [form ]
Solid | [pka]
3.75±0.10(Predicted) | [Appearance]
Off-white to light yellow Solid |
| Hazard Information | Back Directory | [Uses]
(2-Oxopyrrolidin-1-yl)acetic acid is a reagent in the preparation of pyrazolopyridines as PDE4B inhibitors. | [Synthesis]
Benzyl (2-oxopyrrolidin-1-yl) acetate (233 mg, 1.0 mmol) was dissolved in methanol (5 mL) at 23 °C and 10 wt% Pd/C catalyst (100 mg) was added. The reaction mixture was deoxygenated using a vacuum pump and subsequently reacted under hydrogen atmosphere (using a hydrogen balloon).After 3 h, the reaction mixture was filtered through a diatomaceous earth pad and the diatomaceous earth pad was washed with methanol (100 mL). The combined filtrates were concentrated under reduced pressure to afford (2-oxopyrrolidin-1-yl)acetic acid (143 mg, 100% yield). | [References]
[1] Patent: US2006/211603, 2006, A1. Location in patent: Page/Page column 76 |
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