ChemicalBook--->CAS DataBase List--->5416-71-7

5416-71-7

Request For Quotation
5416-71-7 Structure

5416-71-7 Structure
IdentificationBack Directory
[Name]

3,4-DIMETHOXYCHALCONE
[CAS]

5416-71-7
[Synonyms]

AKOS 220-38
3,4-DIMETHOXYCHALCONE
LABOTEST-BB LT00454345
DIMETHOXYCHALCONE,3,4-
3-(3,4-DIMETHOXYPHENYL)-1-PHENYLPROP-2-EN-1-ONE
2-Propen-1-one, 3-(3,4-dimethoxyphenyl)-1-phenyl-
(E)-3-(3,4-DIMETHOXYPHENYL)-1-PHENYLPROP-2-EN-1-ONE
[Molecular Formula]

C17H16O3
[MDL Number]

MFCD00041327
[MOL File]

5416-71-7.mol
[Molecular Weight]

268.31
Chemical PropertiesBack Directory
[Melting point ]

88°C
[Boiling point ]

421.8±45.0 °C(Predicted)
[density ]

1.128±0.06 g/cm3(Predicted)
[form ]

Solid
[color ]

Light yellow to green yellow
Hazard InformationBack Directory
[Uses]

3,4-Dimethoxychalcone is a Caloric restriction mimetics (CRMs). 3,4-Dimethoxychalcone induces the deacetylation of cytoplasmic proteins and stimulates autophagy flux. 3,4-Dimethoxychalcone can be used for cardiac and cancer diseases research[1].
[in vivo]

3,4-Dimethoxychalcone (230 mg/kg for intraperitoneal injection) induces the nuclear translocation of TFEB and TFE3 of liver and heart tissues in Female C57/BL6 mice[1].

[References]

[1] Okolo EN, et al. New chalcone derivatives as potential antimicrobial and antioxidant agent. Sci Rep. 2021 Nov 5;11(1):21781. DOI:10.1038/s41598-021-01292-5
[2] Chen G, et al. 3,4-Dimethoxychalcone induces autophagy through activation of the transcription factors TFE3 and TFEB. EMBO Mol Med. 2019 Nov 7;11(11):e10469. DOI:10.15252/emmm.201910469
Spectrum DetailBack Directory
[Spectrum Detail]

3,4-DIMETHOXYCHALCONE(5416-71-7)1HNMR
5416-71-7 suppliers list
Company Name: JiNan NBT Fine Chemicals Co., Ltd  Gold
Telephone: 18798187137
Website: www.chemicalbook.com/suppliernews_391711.htm
Company Name: Meryer (Shanghai) Chemical Technology Co., Ltd.  
Telephone: 4006356688 18621169109
Website: www.x-labseek.com/
Company Name: ZHEJIANG ZETIAN FINE CHEMICALS CO.,LTD  
Telephone: 0571-87322520 18957127338
Website: http://www.zetchem.com
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Telephone: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Jinan SanZhi Pharmaceutical Technology Co., Ltd.  
Telephone: 15053191807
Website: www.chemicalbook.com/ShowSupplierProductsList19323/0_EN.htm
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Telephone: 15026964105
Website: www.shyuanye.com
Company Name: MQ (shanghai) Pharmaceuticals Co., Ltd.  
Telephone: 13761635123
Website: http://www.linyuepharm.com/
Company Name: Shenzhen Polymeri Biochemical Technology Co., Ltd.  
Telephone: +86-400-002-6226
Website: https://www.rrkchem.com
Company Name: sgtlifesciences pvt ltd  
Telephone: +91-8790379245
Website: https://www.chemicalbook.com/ShowSupplierProductsList1846349/0.htm
Company Name: Career Henan Chemica Co  
Telephone: +86-0371-86658258 +86-13203830695
Website: www.coreychem.com/
Company Name: Chengdu Peter-like Biotechnology Co., Ltd.  
Telephone: 18108052721
Website: https://www.weikeqi-biotech.com/
Company Name: Changzhou Yinghao Technology Development Co., Ltd  
Telephone: 15151934985
Website: http://www.yingsapharm.com/
Company Name: Beijing Stronger Science Co., Ltd.  
Telephone: 0531-88924771 15614660963
Website: https://www.nuoxiansheng.com/
Company Name: Hefei Mokai Pharmaceutical Technology Co., Ltd  
Telephone: 18130062233
Website: www.yxjchem.com/
Company Name: Bide Pharmatech Ltd.  
Telephone: 400-1647117 13681763483
Website: https://www.bidepharm.com/
Company Name: Jiangsu Yaoheng Pharmaceutical Technology Co., Ltd.  
Telephone: 13524761129
Website: https://www.jsyhpharma.com
Company Name: TargetMol Chemicals Inc.  
Telephone: 4008200310 15002144251
Website: https://www.targetmol.cn/
Company Name: Henan Weitixi Chemical Technology Co., Ltd  
Telephone: 0371-53370800 18037197114
Website: https://www.chemicalbook.com/supplier/24683891/
Tags:5416-71-7 Related Product Information
2373-89-9