| Identification | Back Directory | [Name]
ADRIAMYCINOL | [CAS]
54193-28-1 | [Synonyms]
RP-27706
ADRIAMYCINOL
DOXORUBICINOL
antibiotic27706rp
13-dihydroxorubicin
Doxorubicinol (>90%)
13-dihydrodoxorubicin
Doxorubicinol acetate salt
8(r*),10-alpha))-8s-(8-alph
Doxorubicinol (>90%)
(See also D558020)
2-dihdyroxyethyl)-1-methoxy-6,8,11-trihydroxy-lyxo-hexopyranosyl)oxy)-8-((
(8S)-7,8,9,10-Tetrahydro-10α-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-[(S)-1,2-dihydroxyethyl]-1-methoxy-6,8α,11-trihydroxy-5,12-naphthacenedione
5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-[(1S)-1,2-dihydroxyethyl]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S)-
5,12-Naphthacenedione, 10-(3-amino-2,3,6-trideoxy-.alpha.-L-lyxo-hexopyranosyl)oxy-8-(1S)-1,2-dihydroxyethyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S)-
5,12-Naphthacenedione, 7,8,9,10-tetrahydro-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-(1,2-dihydroxyethyl)-1-methoxy-6,8,11-trihydroxy-, (8S-(8-alpha,8(R*),10-alpha))- | [Molecular Formula]
C27H31NO11 | [MDL Number]
MFCD00871943 | [MOL File]
54193-28-1.mol | [Molecular Weight]
545.54 |
| Chemical Properties | Back Directory | [Boiling point ]
828.7±65.0 °C(Predicted) | [density ]
1.61±0.1 g/cm3(Predicted) | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
7.49±0.60(Predicted) | [color ]
Red to Very Dark Red | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
A metabolite of Doxorubicin as neoplasm inhibitor. | [Definition]
ChEBI: Doxorubicinol is a member of the class of tetracenequinones that is the major metabolite of the anthracycline doxorubicin, a chemotherapeutic agent effective against a broad range of malignant neoplasms. It is thought to exhibit cardiotoxic properties. It has a role as a drug metabolite and a cardiotoxic agent. It is a member of p-quinones, an anthracycline antibiotic, a deoxy hexoside, an aminoglycoside, a member of tetracenequinones, a member of phenols, an aromatic ether and a polyol. It derives from a hydride of a tetracene. | [Synthesis]
Adriamycin fermentation broth 2000 liters, add 1N of hydrochloric acid adjusted pH 1.0 for acidification, acidification 3 hours, plate and frame filtration, to get the pre-purified solution 1650 liters, HPLC detection, containing 1000g of adriamycin, chro |
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| Company Name: |
Alfa Chemistry
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| Tel: |
1-516-6625404 |
| Website: |
https://www.alfa-chemistry.com |
| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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