| Identification | Back Directory | [Name]
2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL | [CAS]
5424-47-5 | [Synonyms]
Duloxetine-16
SALOR-INT L158135-1EA
Duloxetine Impurity 18
Duloxetine Impurity 9 HCl
2-THIENYL-2-DIMETHYLAMINOETHYL KETONE HCL
3-DIMETHYLAMINO-1-(2-THIENYL)-1-PROPANONE HCl
3-(dimethylamino)-1-(thiophen-2-yl)propan-1-one
2-Thienyl-2-dimethylaminoethyl ketone hydrochloride
2-[3-(Dimethylamino)propionyl]thiophene Hydrochloride
1-Propanone-3-(diMethylaMino)-1-(2-thienyl)- hydrochloride
3-(Dimethylamino)-1-(2-thienyl)-1-propanoneHydrochloride>
3-(DIMETHYLAMINO)-1-(THIOPHEN-2-YL)PROPAN-1-ONE HYDROCHLORIDE
3-DiMethylaMino-1-(2-thienyl)-1-propanone hydrochloride, 97+%
1-Propanone,3-(diMethylaMino)-1-(2-thienyl)-, hydrochloride (1:1)
3-(N,N-dimethylamino)-1-(thiophen-2-yl)-propan-1-one hydrochloride
1,5-Bis(dimethylamino)-1,5-di(thiophen-2-yl)pentan-3-one hydrochloride
3-Dimethyl amino-1-(2-thienyl)-1-propanone hydrochlorideQ: What is
3-Dimethyl amino-1-(2-thienyl)-1-propanone hydrochloride Q: What is the CAS Number of
3-Dimethyl amino-1-(2-thienyl)-1-propanone hydrochloride Q: What is the storage condition of
3-Dimethyl amino-1-(2-thienyl)-1-propanone hydrochloride | [EINECS(EC#)]
611-117-7 | [Molecular Formula]
C9H14ClNOS | [MDL Number]
MFCD00126349 | [MOL File]
5424-47-5.mol | [Molecular Weight]
219.73 |
| Chemical Properties | Back Directory | [Melting point ]
176.0 to 182.0 °C | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [color ]
White to Almost white | [InChI]
InChI=1S/C9H13NOS.ClH/c1-10(2)6-5-8(11)9-4-3-7-12-9;/h3-4,7H,5-6H2,1-2H3;1H | [InChIKey]
HPVHJPMLORARSR-UHFFFAOYSA-N | [SMILES]
C1(SC=CC=1)C(=O)CCN(C)C.Cl |
| Hazard Information | Back Directory | [Uses]
3-(Dimethylamino)-1-(2-thienyl)-1-propanone, HCl | [Synthesis]
2-Acetylthiophene (128 g, 1.00 mol), dimethylamine hydrochloride (90 g, 1.10 mol), paraformaldehyde (41 g, 1.40 mol), concentrated hydrochloric acid (5 mL), and isopropanol (500 mL) were mixed and heated and refluxed for 6 hours according to the method reported by Robertson [1]. Upon completion of the reaction, the reaction solution was cooled to 0 °C and stirring was continued for 1 hour. Subsequently, the reaction mixture was filtered, the solid product was washed with cold isopropanol and finally dried at 50 °C for 16 h to give 3-dimethylamino-1-(thiophen-2-yl)-propan-1-one hydrochloride (2a). | [References]
[1] Bioorganic Chemistry, 2016, vol. 65, p. 82 - 89
[2] Patent: CN104829587, 2017, B. Location in patent: Paragraph 0050-0052
[3] Tetrahedron Letters, 1990, vol. 31, # 45, p. 7101 - 7104
[4] Patent: EP2305669, 2011, A1. Location in patent: Page/Page column 1.1
[5] Organic Process Research and Development, 2006, vol. 10, # 5, p. 905 - 913 |
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