| Identification | Back Directory | [Name]
Amidothioate | [CAS]
54381-26-9 | [Synonyms]
Mitemate
Amidothioate
Amidothionate
N-Ethylphosphoramidothioic acid O-[2-chloro-4-(methylthio)phenyl] O-methyl
N-Ethylamidothiophosphoric acid O-[2-chloro-4-(methylthio)phenyl]O-methyl ester
Phosphoramidothioic acid, N-ethyl-, O-(2-chloro-4-(methylthio)phenyl) O-methyl ester | [Molecular Formula]
C10H15ClNO2PS2 | [MOL File]
54381-26-9.mol | [Molecular Weight]
311.79 |
| Hazard Information | Back Directory | [Description]
Amidothioate is an obsolete insecticide. Little is known about its chemical properties, environmental fate or its toxicity to humans or biodiversity. | [Production Methods]
Amidothioate is produced through a multi-step process typical of organophosphorus insecticides. The synthesis begins with the preparation of a substituted phenolic intermediate, which is then reacted with methyl phosphorochloridothioate to form the phosphorothioate backbone. This is followed by amidation using ethylamine to introduce the N-ethyl group, creating the phosphoramidothioate structure. The final product undergoes purification through solvent extraction and vacuum distillation, and stabilizers are added to prevent degradation during storage. The process requires strict control of temperature, moisture, and pH due to the high reactivity and toxicity of intermediates. | [Mechanism of action]
Acetylcholinesterase (AchE) inhibitor. | [Pesticide Type]
Insecticide; Acaricide |
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