| Identification | Back Directory | [Name]
TEPA | [CAS]
545-55-1 | [Synonyms]
tef
tapo
TEPA
a6366
nsc9717
sk-3818
SK-3918
KIAA1655
nsc-9717
ent24915
aphoxide
cbc906288
imperonfixert
TEPA (pesticide)
Tri-1-aziridinyl-
ph
triethylenfosforamid
TRIETHYLENEPHOSPHORAMIDE
triaziridinophosphineoxide
triaziridinylphosphineoxide
tris(1-aziridinyl)phosphine
Thyrotroph embryonic factor
triethylenephosphorotriamide
triethylenepyrophosphoramide
triethylenephosphorictriamide
triaethylenphosphorsaeureamid
tri(aziridinyl)phosphineoxide
tris-(1-aziridinyl)fosfinoxid
tri-1-aziridinylphosphineoxide
phosphoricacidtriethyleneimide
tri(1-aziridinyl)phosphineoxide
tris(1-aziridine)phosphineoxide
TRIS-(AZIRIDINYL)-PHOSPHINEOXIDE
1-aziridinylphosphineoxide(tris)
n,n’,n"-triethylene-phosphoramid
n,n’,n"-triethylenephosphoramide
tris(1-aziridinyl)-phosphineoxid
tri(aziridin-1-yl)phosphine oxide
tris-(azir-idinyl)-phos-phinoxide
n,n’,n’’-triethylenephosphoramide
TRIS(1-AZIRIDINYL)PHOSPHINE OXIDE
tris(n-ethylene)phosphorotriamidate
1,1’,1"-phosphinylidynetris-aziridin
1,1’,1’’-phosphinylidynetris-aziridin
1,1’,1’’-phosphinylidynetrisaziridine
n,n’,n"-triethylene-phosphorictriamid
n,n’,n’’-triethylenephosphorictriamide
1-diethyleniminophosphorylethylenimine
1-[bis(aziridin-1-yl)phosphoryl]aziridine
Tri-(1-aziridinyl)phosphine oxide solution
n,n,n’’-tri-1,2-ethanediylphosphorictriamide
n,n’,n’’-tri-1,2-ethanediyl-phosphorictriamid
n,n’,n’’-tri-1,2-ethanediylphosphorictriamide
Anti-TEF, C-Terminal antibody produced in rabbit
Tris-1-aziridinylphosphine oxide or triethylene phosphoramide | [EINECS(EC#)]
208-892-5 | [Molecular Formula]
C6H12N3OP | [MDL Number]
MFCD00081201 | [MOL File]
545-55-1.mol | [Molecular Weight]
173.15 |
| Chemical Properties | Back Directory | [Appearance]
Colorless crystals. Soluble in
water, alcohol, and ether. Combustible. | [Melting point ]
41℃ | [Boiling point ]
299℃ | [density ]
1.47 | [Fp ]
135℃ | [storage temp. ]
-20°C | [solubility ]
Chloroform (Sparingly), Methanol (Slightly) | [form ]
solid | [pka]
2.74±0.20(Predicted) | [Stability:]
Stable. | [biological source]
rabbit | [IARC]
3 (Vol. 9, Sup 7) 1987 | [EPA Substance Registry System]
Aziridine, 1,1',1''-phosphinylidynetris- (545-55-1) |
| Hazard Information | Back Directory | [Chemical Properties]
colourless granules | [Uses]
Used as insect chemosterilant; in dyeing. Antineoplastic. | [Uses]
Insect chemosterilant; in dyeing, creaseproofing and flameproofing textiles; stabilizer for polymers; in photographic emulsion hardening. | [General Description]
An aqueous solution of a colorless crystalline solid. Toxic by skin absorption, ingestion or inhalation. Produces toxic oxides of nitrogen during combustion. Used as a pesticide. | [Reactivity Profile]
TRIS-(1-AZIRIDINYL) PHOSPHINE OXIDE may react with aqueous solutions of acids or strong bases. Undergoes slow decomposition in water, not considered hazardous. Polymerizes violently at about 255°F. Acid fumes also cause polymerization at ordinary temperatures [USCG, 1999]. May produce highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. | [Health Hazard]
Inhalation (unlikely unless a heavy mist is formed) causes symptoms similar to those observed after ingestion. Contact with liquid or powder causes irritation of eyes and (on prolonged contact) irritation and burns of skin. Burns are slow to develop and slow to heal. May sensitize on repeated contact. Ingestion causes depression, anorexia, and diarrhea, appearing 2-3 days before death, followed by terminal dyspnea, incoordination, epistaxis, salivation, prostration and cyanosis. | [Fire Hazard]
Special Hazards of Combustion Products: Phosphoric acid mist may form in fire. Toxic oxides of nitrogen may form. | [Definition]
ChEBI: Tris(1-aziridinyl)phosphine oxide is a phosphoramide. |
| Safety Data | Back Directory | [RIDADR ]
2811 | [WGK Germany ]
nwg | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Storage Class]
10 - Combustible liquids | [Safety Profile]
Poison by ingestion,
skin contact, intravenous, and
intraperitoneal routes. Experimental
teratogenic and reproductive effects.
Questionable carcinogen with experimental
carcinogenic and neoplastigenic data.
Human mutation data reported. A corrosive
irritant to the skin, eyes, and mucous
membranes. When heated to decomposition
it emits very toxic fumes of POx and NOx.
Used as an acaricide and in the permanentpress
treatment of cotton. | [Hazardous Substances Data]
545-55-1(Hazardous Substances Data) | [Toxicity]
LD50 orally in male rats: 37 mg/kg (Gaines) |
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