ChemicalBook--->CAS DataBase List--->54518-92-2

54518-92-2

54518-92-2 Structure

54518-92-2 Structure
IdentificationBack Directory
[Name]

L-LEUCINE CHLOROMETHYL KETONE HYDROCHLORIDE
[CAS]

54518-92-2
[Synonyms]

Leu-CMK HCl
L-Leu-CMK·HCl
H-LEU-CMK HCL
H-Leu-chloromethylketone
H-LEU-CHLOROMETHYLKETONE HCL
L-leucinechloromethylketoneHCl
LEUCINE-CHLOROMETHYLKETONE HCL
H-Leu-Chloromethylketone hydrochloride
L-LEUCINE CHLOROMETHYL KETONE HYDROCHLORIDE
H-Leu-CMK.HClL-Leucine chloroMethyl ketone hydr
(S)-3-AMino-1-chloro-5-Methylhexan-2-one hydrochloride
(S)-3-Amino-1-chloro-5-methyl-2-hexanone hydrochloride
2-Hexanone,3-aMino-1-chloro-5-Methyl-, hydrochloride, (3S)- (9CI)
[Molecular Formula]

C7H15Cl2NO
[MDL Number]

MFCD00238011
[MOL File]

54518-92-2.mol
[Molecular Weight]

200.11
Chemical PropertiesBack Directory
[storage temp. ]

Inert atmosphere,2-8°C
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[color ]

white to off-white
[InChI]

1S/C7H14ClNO.ClH/c1-5(2)3-6(9)7(10)4-8;/h5-6H,3-4,9H2,1-2H3;1H/t6-;/m0./s1
[InChIKey]

DRZZRBOLWKRHPF-RGMNGODLSA-N
[SMILES]

Cl.CC(C)C[C@H](N)C(=O)CCl
Safety DataBack Directory
[WGK Germany ]

3
[Storage Class]

13 - Non Combustible Solids
Hazard InformationBack Directory
[Chemical Properties]

White solid
[Uses]

L-Leucine chloromethyl ketone HCl
[Biochem/physiol Actions]

L-Leucine chloromethyl ketone (Leu-CMK) is used as a lysosomal cysteine protease inhibitor and as an insulin-like stimulator of lipid synthesis. L-Leucine chloromethyl ketone (Leu-CMK) may be acetylated to generate acetylleucine chloromethyl ketone, an inhibitor of acylpeptide hydrolase.
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