| Identification | Back Directory | [Name]
methyl protogracillin | [CAS]
54522-53-1 | [Synonyms]
NSC 698792
Kikubasaponin
methyl protogracillin
22-O-Methylprotogracillin
b-D-Glucopyranoside, (3b,22a,25R)-26-(b-D-glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl O-6-deoxy-a-L-mannopyranosyl-(12)-O-[b-D-glucopyranosyl-(13)]-
β-D-Glucopyranoside, (3β,22α,25R)-26-(β-D-glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]- | [EINECS(EC#)]
300-008-5 | [Molecular Formula]
C52H86O23 | [MDL Number]
MFCD32197353 | [MOL File]
54522-53-1.mol | [Molecular Weight]
1079.24 |
| Hazard Information | Back Directory | [Uses]
Methyl protogracillin (NSC-698793), isolated from the roots of Dioscorea opposite Thunb, exhibits strong anti-cancer activity[1]. | [References]
[1] Hu K, et al. The cytotoxicity of methyl protoneogracillin (NSC-698793) and gracillin (NSC-698787), two steroidal saponins from the rhizomes of Dioscorea collettii var. hypoglauca, against human cancer cells in vitro. Phytother Res. 2003 Jun;17(6):620-6. DOI:10.1002/ptr.1211 |
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