| Identification | Back Directory | [Name]
3-(2-chlorophenyl)-N-(4-{[3-(2-chlorophenyl)acryloyl]amino}butyl)acrylamide | [CAS]
547731-67-9 | [Synonyms]
BCPA
3-(2-chlorophenyl)-N-(4-{[3-(2-chlorophenyl)acryloyl]amino}butyl)acrylamide | [Molecular Formula]
C22H22Cl2N2O2 | [MOL File]
547731-67-9.mol | [Molecular Weight]
417.328 |
| Hazard Information | Back Directory | [Uses]
BCPA is a Pin1 regulator without cytotoxicity. BCPA attenuates the reduction of Pin1 protein to inhibit receptor activator of RANKL-induced osteoclastogenesis. BCPA regulates osteoclast activation, used to osteoporosis research[1]. | [References]
[1] Cho E, et al. BCPA {N, N′-1, 4-Butanediylbis [3-(2-chlorophenyl) acrylamide]} Inhibits osteoclast differentiation through increased retention of peptidyl-prolyl cis-trans isomerase never in mitosis A-interacting 1[J]. International Journal of Molecular Sciences, 2018, 19(11): 3436. |
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