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548762-66-9

548762-66-9 Structure

548762-66-9 Structure
IdentificationBack Directory
[Name]

(2S,5R)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
[CAS]

548762-66-9
[Synonyms]

(2S,5R)-1-N-BOC-2,5-DIMETHYLPIPERAZINE
(2S,5R)-1-Boc-2,5-diMethylpiperazine-HCl
(2S,5R)-2,5-Dimethylpiperazine,N1-BOCprotected
(2S,5R)-1-Boc-2,5-diMethylpiperazine hydrochloride
tert-butyl (2S,5R)-2,5-diMethylpiperazine-1-carboxylate
(2S,5R)-tert-Butyl 2,5-diMethylpiperazine-1-carboxylate
(2S,5R)-2,5-Dimethyl-1-piperazinecarboxylic acid tert-butyl ester
(2S,5R)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
tert-butyl (2S,5R)-2,5-dimethylpiperazine-1-carboxylate hydrochloride
(2S,5R)-tert-Butyl 2,5-DiMethylpiperazine-1-carboxylate hydrochloride
(2|S|,5S|S|)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
(2S,5R)-2,5-DiMethyl-1-piperazinecarboxylic Acid 1,1-DiMethylethyl Ester
1-Piperazinecarboxylic acid, 2,5-dimethyl-, 1,1-dimethylethyl ester, (2S,5R)-
(2S,5R)-1-Boc-2,5-diMethylpiperazine/(2S,5R)-tert-butyl 2,5-diMethylpiperazine-1-carboxylate
[Molecular Formula]

C11H22N2O2
[MDL Number]

MFCD08686667
[MOL File]

548762-66-9.mol
[Molecular Weight]

214.3
Questions And AnswerBack Directory
[Synthesis]

The target compound was prepared using (2S,5R)-2,5-dimethylpiperazine and tert-butyl dicarbonate as starting materials.

Synthesis of 548762-66-9

Chemical PropertiesBack Directory
[Boiling point ]

280℃
[density ]

0.970
[Fp ]

123℃
[storage temp. ]

Keep in dark place,Sealed in dry,2-8°C
[pka]

8.55±0.60(Predicted)
[InChI]

InChI=1S/C11H22N2O2/c1-8-7-13(9(2)6-12-8)10(14)15-11(3,4)5/h8-9,12H,6-7H2,1-5H3/t8-,9+/m1/s1
[InChIKey]

PGZCVLUQTJRRAA-BDAKNGLRSA-N
[SMILES]

N1(C(OC(C)(C)C)=O)C[C@@H](C)NC[C@@H]1C
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P271-P261-P280
[HS Code ]

2933599590
Hazard InformationBack Directory
[Uses]

An intermediate used in the synthesis of a series of derivatives of the 4-fluorobenzyl dimethylpiperazine-indole class of p38α MAP kinase inhibitors with improved pharmacokinetic properties. An intermediate used in the enantioselective synthesis of (-)-1-allyl-(2S,5R)-dimethylpiperazine (I), an important intermediate in the synthesis of δ-opioid receptor ligands.
Spectrum DetailBack Directory
[Spectrum Detail]

(2S,5R)-2,5-DIMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER(548762-66-9)1HNMR
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