| Identification | Back Directory | [Name]
SEMPERVIRINE NITRATE | [CAS]
549-92-8 | [Synonyms]
sempervirine
SEMPERVIRINE NITRATE
SEMPERVIRINE NITRATE WITH HPLC
1,2,3,4-tetrahydroisoquinolino[3,2-a]$b-carboline | [Molecular Formula]
C19H13N3O3 | [MDL Number]
MFCD00017723 | [MOL File]
549-92-8.mol | [Molecular Weight]
331.32 |
| Hazard Information | Back Directory | [Uses]
Sempervirine is an indole alkaloid isolated from Gelsemium sempervirens with anti-tumor activities. Sempervirine is against sempervirine-sensitive tumor cells with EC50 values of 2.7 μM, 1.77 μM, and 1.96 μM for Raji, MDA-MB-231 and HeLa cells, respectively[2]. | [Definition]
ChEBI: Sempervirine is a member of beta-carbolines. | [References]
[1] Noriyuki Kogure,?et al. Total synthesis and full NMR assignment of ourouparine, a yohimbane-type indole alkaloid isolated from Gelsemium sempervirens. Journal of Natural Medicines?volume |
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