| Identification | Back Directory | [Name]
Betanidine | [CAS]
55-73-2 | [Synonyms]
BETANIDIN
Betanidine
Bethanidine
Betanidine USP/EP/BP
2-benzyl-1,3-diMethylguanidine
1-Benzyl-2,3-dimethylguanidine
N,N'-Dimethyl-N''-(phenylmethyl)guanidine
Guanidine, N,N''-dimethyl-N'-(phenylmethyl)- | [Molecular Formula]
C10H15N3 | [MOL File]
55-73-2.mol | [Molecular Weight]
177.25 |
| Chemical Properties | Back Directory | [Melting point ]
195-197° | [Boiling point ]
299.18°C (rough estimate) | [density ]
0.9826 (rough estimate) | [refractive index ]
1.4800 (estimate) | [pka]
pKa 10.6 (Uncertain) |
| Hazard Information | Back Directory | [Originator]
Bendogen,Lagap
Pharmaceuticals SA | [Uses]
Betanidine is a betacyanin and an aglycone of the beet dye betanin. | [Definition]
ChEBI: Bethanidine is a member of guanidines. It has a role as an adrenergic antagonist and an antihypertensive agent. | [Manufacturing Process]
A mixture of 2-bromobenzylamine (12.5 g) and S-methylthiouronium sulfate
(10 g) in water (20 ml) was heated for 1.5 hours on a steam bath in a hood,
during which methylmercaptan escaped (as evidenced by a foul odour). The
reaction mixture was then cooled and diluted with ethanol (100 ml). A
colourless solid of 2-bromobenzylguanidine sulfate was separeted, and washed
with ethanol. This solid melted at 230-232°C; it was recrystallized from water
and then melted at 247-248°C. By action of a basic agent the salt obtained
may be converted into free base. | [Therapeutic Function]
Antihypertensive |
|
| Company Name: |
Leancare Ltd.
|
| Tel: |
+33 962096793 |
| Website: |
www.leancare.co.uk |
|