| Identification | Back Directory | [Name]
NEBULARINE | [CAS]
550-33-4 | [Synonyms]
NSC65423
Purinosine
NEBULARINE
ribosyl-purin
ribosylpurine
PURINE RIBOSIDE
Ribosyl-isopurine
6-deaMinoadenosine
PURINE RIBONUCLEOSIDE
9-purineribonucleoside
Nebularine (high purity)
Purine-9-D-Ribofuranoside
9-beta-D-Ribosyl-9H-purine
9-β-D-Ribofuranosyl-9H-purine
PURINE 9BETA-D-RIBOFURANOSIDE
9-(beta-d-ribofuranosyl)purine
9-beta-d-ribofuranosyl-9h-purin
9-beta-d-ribofuranosyl-9h-purine
9H-Purine, 9-.beta.-D-ribofuranosyl-
1-(9H-Purine-9-yl)-1-deoxy-β-D-ribofuranose | [EINECS(EC#)]
208-981-9 | [Molecular Formula]
C10H12N4O4 | [MDL Number]
MFCD00022819 | [MOL File]
550-33-4.mol | [Molecular Weight]
252.23 |
| Chemical Properties | Back Directory | [Appearance]
Crystalline Solid | [Melting point ]
181-182°C | [alpha ]
D25 -48.6° (H2O) | [Boiling point ]
395.4°C (rough estimate) | [density ]
1.3402 (rough estimate) | [refractive index ]
1.6500 (estimate) | [storage temp. ]
2-8°C | [solubility ]
DMSO (Slightly), Ethanol, Methanol (Slightly) | [form ]
Solid | [pka]
13.13±0.70(Predicted) | [color ]
Pale Beige to Beige | [Merck ]
13,6461 | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Uses]
Shown to have inhibitory effects against mouse Sarcoma 180 and mycobacteria | [Definition]
ChEBI: A purine ribonucleoside that is 9H-purine attached to a beta-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage. | [Description]
This purine base is produced by Agarius nebularis Batsch. (Syn. Clitocybe
nebularis). It is laevorotatory with [α]25D - 48.6° (c 1.0, H20). | [storage]
+4°C | [Purification Methods]
Nebularine is recrystallised from butanone/MeOH or EtOH and forms a MeOH photo-adduct. It is a strong inhibitor of adenosine deaminase [EC 3.5.4.4]. [Nair & Weichert Bioorg Chem 9 423 1980, Lfgren et al. Acta Chem Scand 7 225 1953, UV: Brown & Weliky J Biol Chem 204 1019 1953, Beilstein 26 III/IV 1740.]
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