| Identification | Back Directory | [Name]
2-[(5-benzyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]-N-(2-methoxyphenyl)acetamide | [CAS]
550301-63-8 | [Synonyms]
WAY-323061
2-((5-Benzyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio)-N-(2-methoxyphenyl)acetamide
2-[(5-benzyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)sulfanyl]-N-(2-methoxyphenyl)acetamide
Acetamide, N-(2-methoxyphenyl)-2-[[5-(phenylmethyl)-5H-1,2,4-triazino[5,6-b]indol-3-yl]thio]- | [Molecular Formula]
C25H21N5O2S | [MOL File]
550301-63-8.mol | [Molecular Weight]
455.53 |
| Hazard Information | Back Directory | [Uses]
SR94, a SR17 derivative, is a SIRT2 inhibitor that contains an arbitrary 6-member ring and different R2 groups. SR94 is promising for research of cancer, ischemia-reperfusion and neurodegenerative diseases[1]. | [IC 50]
SIRT2 | [References]
[1] Huang S, et al. Discovery of New SIRT2 Inhibitors by Utilizing a Consensus Docking/Scoring Strategy and Structure-Activity Relationship Analysis. J Chem Inf Model. 2017 Apr 24;57(4):669-679. DOI:10.1021/acs.jcim.6b00714 |
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