| Identification | Back Directory | [Name]
tetrahydroxyl diphenylethylene-2-o-glucoside | [CAS]
55327-45-2 | [Synonyms]
tetrahydroxyl diphenylethylene-2-o-gluco
tetrahydroxyl diphenylethylene-2-o-glucoside
2,3,5,4'-Tetrahydroxytoluylene-2-β-D-glucoside
2,3,5,4'-Tetrahydroxytoluylene-2-beta-D-glucoside
2,3,5,4-tetrahydroxyl diphenylethylene -2-o-glucos
2,3,5,4-tetrahydroxyl diphenylethylene-2-o-glucoside
2,3,5,4'-Tetrahydroxyldiphenylethylene 2-O-β-D-glucoside
2,3,5,4'-Tetrahydroxyl-diphenylethylene-2-O-β-D-glucoside
2,3,5,4'-Tetrahydroxyl-diphenylethylene-2-O-beta-D-glucoside
β-D-Glucopyranoside, 2,4-dihydroxy-6-[2-(4-hydroxyphenyl)ethenyl]phenyl
2,3,5,4'-TETRAHYDROXYTOLUYLENE-2-BETA-D-GLUCOSIDE; 2,3,5,4'-TETRAHYDROXYL-DIPHENYLETHYLENE-2-O-BETA-D-GLUCOSIDE | [Molecular Formula]
C20H22O9 | [MOL File]
55327-45-2.mol | [Molecular Weight]
406.38 |
| Hazard Information | Back Directory | [Uses]
2,3,4',5-Tetrahydroxystilbene 2-O-β-D-glucoside (TSG) is an active product that can be extracted from Polygonum multiflorum Thunb. TSG has anti-inflammatory, antioxidative, anti-atherosclerotic, anti-apoptotic, and free radical scavenging activities, TSG is also indicated to facilitate long-term potentiation and learning and memory in both normal and pathological conditions[1][2]. | [Definition]
ChEBI: (E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside is a stilbenoid that is trans-stilbene which has been substituted by hydroxy groups at positions 2, 3, 5, and 4', and in which the hydroxy group at positon 2 has then been converted to the corresponding the beta-D-glucoside. It has a role as an antioxidant, a cyclooxygenase 2 inhibitor, an anti-inflammatory agent, a cardioprotective agent, a platelet aggregation inhibitor and an apoptosis inhibitor. It is a stilbenoid, a beta-D-glucoside and a member of resorcinols. | [References]
[1] Y Kimura, et al. Effects of stilbene components of roots of Polygonum ssp. on liver injury in peroxidized oil-fed rats. Planta Med. 1983 Sep;49(1):51-4. DOI:10.1055/s-2007-969810
[2] Wu J, et al. Current pharmacological developments in 2,3,4',5-tetrahydroxystilbene 2-O-β-D-glucoside (TSG). Eur J Pharmacol. 2017 Sep 15;811:21-29. DOI:10.1016/j.ejphar.2017.05.037 |
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