| Identification | Back Directory | [Name]
(+)-BUTACLAMOL HYDROCHLORIDE | [CAS]
55528-07-9 | [Synonyms]
(+)-Butaclamol
(+)-BUTACLAMOL HYDROCHLORIDE
(+)-BUTACLAMOL HYDROCHLORIDE DOPAMINE AN TAGONIST | [Molecular Formula]
C25H32ClNO | [MDL Number]
MFCD00082307 | [MOL File]
55528-07-9.mol | [Molecular Weight]
397.98 |
| Chemical Properties | Back Directory | [solubility ]
H2O: 0.25 mg/mL solutions should be freshly prepared. | [form ]
solid | [color ]
white | [Optical Rotation]
[α]27/D +222° in methanol(lit.) | [InChI]
1S/C25H31NO.ClH/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25;/h4-10,21-22,27H,11-16H2,1-3H3;1H/t21-,22-,25-;/m0./s1 | [InChIKey]
QZRUMKUMFJJARD-AAJWHBHYSA-N | [SMILES]
Cl[H].[H][C@@]12C[C@@](O)(CCN1C[C@@]3([H])c4ccccc4CCc5cccc2c35)C(C)(C)C |
| Hazard Information | Back Directory | [Uses]
(+)-Butaclamol hydrochloride has been used as a dopamine receptor blocker in:
- dissected brain sections
- striatum of Parkinson′s disease specimens
- human embryonic kidney cells (HEK293 cells)
- mice striatal tissue
| [Biochem/physiol Actions]
(+)-Butaclamol is a dopamine receptor antagonist and is an active enantiomer. |
|
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