| Identification | Back Directory | [Name]
(R)-N,N-DIMETHYL-1-[(S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLAMINE | [CAS]
55700-44-2 | [Synonyms]
Josiphos
(R)-(S)-PPFA
Josiphos SL-0000-2
)-N,N-DiMethyl-1-[(S)-2-(diphenylphosphino)ferro
(-)-(R)-N,N-dimethyl-1-((S)-2-(diphenyl-phosphino
(R)-N,N-Dimethyl-1-((S)-2-(diphenylphosphino)ferro
(1R)-1-(2-diphenylphosphanylcyclopentyl)-N,N-dimethylethanamine
(R)-N,N-Dimethyl-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethy...
)-N,N-DiMethyl-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethylaMine
(R)-(-)-N,N-DIMETHYL-1-(2-DIPHENYLPHOSPHINO)FERROCENYLETHYLAMINE
(R)-N,N-DIMETHYL-1-[(S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLAMINE
(S)-1-[(R)-1-(Dimethylamino)ethyl]-2-(diphenylphosphino) ferrocene
(R) -NN-dimethyl-1-((S) -2-diphenylphosphorus) ferrocene) ethylamine
(R)-N,N-Dimethyl-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethylamine>
(R)-N,N-Dimethyl-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethylamine,96%
(-)-(R)-N,N-DIMETHYL-1-[(S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLAMINE
(R) - (-) - N, N- diMethyl-1- (2-biphenyl-phosphino) ferrocene ethylaMine
(R)-(-)-N,N-Dimethyl-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethylamine, 97%,
(R)-N,N-Dimethyl-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethylamine, 96%, for synthesis | [EINECS(EC#)]
633-502-9 | [Molecular Formula]
C26H28FeNP 10* | [MDL Number]
MFCD00075286 | [MOL File]
55700-44-2.mol | [Molecular Weight]
441.33 |
| Chemical Properties | Back Directory | [Melting point ]
141-143 °C(lit.)
| [alpha ]
-355 º (C=0.6 IN ETOH) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [form ]
solid | [color ]
Light yellow to Yellow to Orange | [Optical Rotation]
[α]20/D 355°, c = 0.6 in ethanol | [Water Solubility ]
Insoluble in water. | [Sensitive ]
Air Sensitive | [InChI]
1S/C21H23NP.C5H5.Fe/c1-17(22(2)3)20-15-10-16-21(20)23(18-11-6-4-7-12-18)19-13-8-5-9-14-19;1-2-4-5-3-1;/h4-17H,1-3H3;1-5H;/t17-;;/m1../s1 | [InChIKey]
RCAFPSZHKFOLEE-ZEECNFPPSA-N | [SMILES]
[Fe].[CH]1[CH][CH][CH][CH]1.C[C@H]([C]2[CH][CH][CH][C]2P(c3ccccc3)c4ccccc4)N(C)C |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
20/21/22-36/37/38 | [Safety Statements ]
26-36-36/37/38 | [RIDADR ]
3288 | [WGK Germany ]
3
| [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29319090 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
Yellow solid | [Uses]
Ligand used in the enantioselective vinylation of aldehydes. | [Application]
(R)-N,N-dimethyl-1-[(s)-2-(diphenylphosphino)ferrocenyl]ethylamine is an effective chiral phosphine ligand for nickel- or palladium-catalyzed asymmetric cross-couplings of organomagnesium or zinc reagents with alkenyl bromides and for palladium-catalyzed asymmetric hydrosilylations of 1,3-dienes. | [reaction suitability]
reaction type: Asymmetric synthesis
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand
reaction type: Cross Couplings | [storage]
stable in air for years, but best kept sealed in a refrigerator. |
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