Capuride (VPA, 38-107 mg/kg p.o.) shows anticonvulsant activity in MES and scMet induced seizures rats[2].
Capuride (p.o., rats) shows neurotoxicity with an ED50 of 232 mg/kg[2].
Capuride (49-71 mg/kg, i.p.) shows anticonvulsant activity in 6 Hz Psychomotor seizure mice[2].
| Animal Model: | Electrically (MES) and chemically (scMet) induced seizures in rats[2] |
| Dosage: | 38-107 mg/kg |
| Administration: | Oral administration (p.o.) |
| Result: | ED50s: 54 mg/kg (MES model), 77 mg/kg (scMet model). |