| Identification | Back Directory | [Name]
4-THIO-2'-DEOXYURIDINE | [CAS]
5580-20-1 | [Synonyms]
4-Thiodeoxyuridine
2’-Deoxy-4-thiouridine
Uridine, 2'-deoxy-4-thio-
1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-thioxo-3,4-dihydropyrimidin-2(1H)-one | [Molecular Formula]
C9H12N2O4S | [MDL Number]
MFCD00058457 | [MOL File]
5580-20-1.mol | [Molecular Weight]
244.27 |
| Hazard Information | Back Directory | [Uses]
4-Thio-2’-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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