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5586-87-8

5586-87-8 Structure

5586-87-8 Structure
IdentificationBack Directory
[Name]

N-(3-chloropropyl)-alpha-methylphenethylamine hydrochloride
[CAS]

5586-87-8
[Synonyms]

Incital
Doracil
Rondimen
Pondinil
Pondinol
R 4-5282
Ro 4-5282
NSC 133749
Mefenorex HCl
IDHNGYVCZUQHFV-UHFFFAOYSA-N
N-ChloropropylaMphetaMine Hydrochloride
N-(3-Chloropropyl)-α-MethylbenzeneethanaMine Hydrochloride
N-(3-chloropropyl)-alpha-methylphenethylamine hydrochloride
N-(3-Chloropropyl)-1-Methyl-2-phenylethylaMine Hydrochloride
[EINECS(EC#)]

226-985-9
[Molecular Formula]

C12H19Cl2N
[MDL Number]

MFCD00242765
[MOL File]

5586-87-8.mol
[Molecular Weight]

248.192
Chemical PropertiesBack Directory
[Melting point ]

128-130°
Hazard InformationBack Directory
[Originator]

Pondinil,Roche,France,1970
[Uses]

This is a controlled substance (stimulant). Anorexic.
[Manufacturing Process]

9.5 parts of β-chloropropionaldehyde were added slowly, at a temperature of 0°C to a solution of 31.5 parts of 1-phenyl-2-aminopropane in 150 parts of methanol. Thereafter, 0.2 part of platinum oxide was added to the reaction mixture following which the mixture was reacted with hydrogen, in a shaking vessel, until the theoretical quantity of hydrogen had been taken up. When the hydrogenation reaction was completed, the catalyst was removed by filtration and the filtrate neutralized with hydrochloric acid. Subsequently, the filtrate was evaporated to dryness and recrystallized from isopropyl alcohol. The thus-obtained N-(3-chloropropyl)-α-methylphenethylamine hydrochloride melted at 128°C to 130°C.
[Therapeutic Function]

Anorexic
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