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559-51-3

559-51-3 Structure

559-51-3 Structure
IdentificationBack Directory
[Name]

kopsinine
[CAS]

559-51-3
[Synonyms]

kopsinine
(2α,5α)-Aspidofractinine-3β-carboxylic acid methyl ester
2,21-Cycloaspidospermidine-3-carboxylic acid, methyl ester, (3β,5α,12R,19α)-
[Molecular Formula]

C21H26N2O2
[MDL Number]

MFCD00879829
[MOL File]

559-51-3.mol
[Molecular Weight]

338.44
Chemical PropertiesBack Directory
[Melting point ]

104-5°C
[Boiling point ]

497.4±45.0 °C(Predicted)
[density ]

1.29±0.1 g/cm3(Predicted)
[pka]

9.38±0.40(Predicted)
Hazard InformationBack Directory
[Description]

Present in Kopsia longijlora, this base is purified by crystallization from light petroleum when it forms colourless crystals. It has [α]23D - 76.9° (c 2.09, CHC1 3). It forms a crystalline dihydrochloride with m.p. 253-4°C, a mono_x0002_methiodide, m.p. 265-6°C and a monopicrate, m.p. 222-3°C. The N-formyl derivative is identical with aspidofractine (q.v.).
[Uses]

Kopsinine is an indole alkaloid extracted from periwinkle flowers[1].
[Definition]

ChEBI: A natural product found in Kopsia grandifolia.
[References]

Crow, Michael., Austral. 1. Chem., 8, 129 (1955)
Kump, Schmid., Helv. Chim. Acta, 44, 1503 (1961)
Kump et al., ibid, 45, 854 (1962)
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