| Identification | Back Directory | [Name]
HOMO-GAMMA-LINOLEICACID | [CAS]
5598-38-9 | [Synonyms]
XSXIVVZCUAHUJO-HZJYTTRNSA-N
all-cis-11,14-Eicosadienoic acid
11-cis,14-cis-Eicosadienoic acid
(11Z,14Z)-icosa-11,14-dienoic acid
Eicosadienoic acid(cis-11,14)(C20:2)
11,14-Eicosadienoic acid, (11Z,14Z)- | [Molecular Formula]
C20H36O2 | [MDL Number]
MFCD00673431 | [MOL File]
5598-38-9.mol | [Molecular Weight]
308.5 |
| Chemical Properties | Back Directory | [Boiling point ]
462.1±0.0 °C(Predicted) | [density ]
0.905±0.06 g/cm3(Predicted) | [solubility ]
0.15 M Tris-HCl pH 8.5: >1 mg/ml (from Oleic Acid)
DMF: >100 mg/ml (from Oleic Acid)
DMSO: >100 mg/ml (from Oleic Acid)
Ethanol: >100 mg/ml (from Oleic Acid)PBS pH 7.2: <100 µg/ml (from Oleic Acid) | [form ]
Liquid | [pka]
4.78±0.10(Predicted) | [color ]
Colorless to light yellow | [LogP]
8.240 (est) |
| Hazard Information | Back Directory | [Uses]
11(Z),14(Z)-Eicosadienoic acid is a unsaturated fattly acid that inhibits [3H] leukotriene B4 (LTB4) binding to pig neutrophil membranes with a Ki of 3 μM. 11(Z),14(Z)-Eicosadienoic acid has inflammatory activities[1][2]. | [Definition]
ChEBI: (11Z,14Z)-icosadienoic acid is an icosadienoic acid with double bonds at positions 11 and 14 (both Z). It has a role as a metabolite. It is a conjugate acid of an (11Z,14Z)-icosadienoate. It derives from a hydride of an icosanoic acid. | [References]
[1] Carballeira NM, et al. Identification of naturally occurring trans, trans delta 5,9 fatty acids from the sponge Plakortis halichondroides. Lipids. 1990 Dec;25(12):835-40. DOI:10.1007/BF02535906
[2] Yagaloff KA, et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids. 1995 May;52(5):293-7. DOI:10.1016/0952-3278(95)90029-2 |
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