ChemicalBook--->CAS DataBase List--->56-29-1

56-29-1

56-29-1 Structure

56-29-1 Structure
IdentificationBack Directory
[Name]

HEXOBARBITAL
[CAS]

56-29-1
[Synonyms]

EVIPAL
Dorico
Evipan
Toleran
Hexenal
Citodon
Citopan
Cyclonal
Narcosan
Sombulex
Cyclopan
Enhexymal
Somnalert
Barbidorm
Noctivane
Sombucaps
Methexenyl
Cyclohexemal
Esobarbitale
HEXOBARBITAL
Hexabarbital
Hexobarbitone
hexanastaboral
Hexanastab oral
Methylhexabital
Methylhexabarbital
hexenal(barbiturate)
Hexenal (barbiturate)
LABOTEST-BB LT00244803
component of Percobarb
Hexobarbital solution
Hexobarbital CIII (500 mg)
Hexobarbital CIII (1307003)
Hexobarbital Solution, 100ppm
hexobarbital methanol solution
hexobarbital--deascheduleiiiitem
Hexobarbital (base and/or unspecified salts)
1,5-dimethyl-5-(1-cyclohexenyl)barbituricacid
5-[1-CYCLOHEXENYL]-1,5-DIMETHYLBARBITURIC ACID
1,5-Dimethyl-5-(1-cyclohexenyl)barbituric acid
5-(Cyclohexen-1-yl)-1,5-dimethylbarbitursaeure
n-methyl-5-cyclohexenyl-5-methylbarbituricacid
5-(cyclohex-1-enyl)-1,5-dimethylbarbituric acid
N-Methyl-5-cyclohexenyl-5-methylbarbituric acid
5-(Cyclohexen-1-yl)-1,5-dimethylbarbituric acid
5-(1-cyclohexen-1-yl)-1,5-dimethyl-barbituricaci
5-(1-cyclohexen-1-yl)-1,5-dimethylbarbituricacid
5-(1-Cyclohexene-1-yl)-1,5-dimethylbarbituricacid
5-(1-Cyclohexen-1-yl)-1,5-dimethylbarbituric acid
5-(1-cyclohexenyl-1)-1-methyl-5-methylbarbituricacid
Barbituric acid, 5-(1-cyclohexen-1-yl)-1,5-dimethyl-
5-(1-Cyclohexenyl-1)-1-methyl-5-methylbarbituric acid
5-(1-Cyclohexenyl)-1,5-dimethylbarbituric acid, Evipal
5-cyclohexen-1-yl-1,5-dimethyl-1,3-diazinane-2,4,6-trione
5-(delta-1,2-cyclohexenyl)-5-methyl-N-methyl-barbitursaeure
6(1h,3h,5h)-pyrimidinetrione,5-(1-cyclohexen-1-yl)-1,5-dimethyl-4
5-(1-Cyclohexen-1-yl)-1,5-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-cyclohexen-1-yl)-1,5-dimethyl-
[EINECS(EC#)]

200-264-9
[Molecular Formula]

C12H16N2O3
[MDL Number]

MFCD00057562
[MOL File]

56-29-1.mol
[Molecular Weight]

236.27
Chemical PropertiesBack Directory
[Appearance]

White crystals.
[Melting point ]

145-147°
[Boiling point ]

378.73°C (rough estimate)
[density ]

1.1623 (rough estimate)
[refractive index ]

1.5460 (estimate)
[Fp ]

11 °C
[storage temp. ]

2-8°C
[pka]

7.99±0.10(Predicted)
[Water Solubility ]

434.7mg/L(25 ºC)
[Uses]

Medicine (sedative).
[EPA Substance Registry System]

Hexobarbital (56-29-1)
Hazard InformationBack Directory
[Chemical Properties]

White crystals.
[Definition]

ChEBI: A member of the class of barbiturates taht is barbituric acid substituted at N-1 by methyl and at C-5 by methyl and cyclohex-1-enyl groups.
[Description]

Hexobarbital, 5-(cyclohexen-1- yl)-1,5-dimethylbarbituric acid,Mr 236.26. The acid forms colorless crystals that turn pink on exposure to light, mp 146 ?C. A 10 % aqueous solution of the sodium salt, Mr 258.25, has a pH of 11.5.
[Brand name]

Cyclonal sodium;Cyclopan;Dorico soluble;Eviderm;Evipal sodium;Evipanl;Hexanal;Hexanastab oral.
[World Health Organization (WHO)]

Hexobarbital is a short-acting barbiturate. See WHO comment for barbiturates.
[Clinical Use]

Methohexital sodium is a short-acting anesthetic administered intravenously. It is very potent and has the shortest duration of action among the barbiturates used. A disturbing factor is that rather frequently it causes hiccups directly after injection. Patients are reported to recover rapidly from anesthesia. Abuse can lead to addiction.
[Synthesis]

Hexobarbital sodium is prepared by condensation of methyl(cyclohexen-1-yl)cyanoacetic ester with dicyanodiamide to 5-(cyclohexen- 1-yl)-5-methyl-2,6-diimino-3-cyanobarbituric acid, followed by methylation with dimethyl sulfate and hydrolysis with 25 % sulfuric acid .
Safety DataBack Directory
[Hazard Codes ]

Xn,T,F
[Risk Statements ]

22-39/23/24/25-23/24/25-11
[Safety Statements ]

36/37/39-45-36/37-16-7
[RIDADR ]

3249
[WGK Germany ]

3
[RTECS ]

CQ2625000
[HazardClass ]

6.1(b)
[PackingGroup ]

III
Spectrum DetailBack Directory
[Spectrum Detail]

HEXOBARBITAL(56-29-1)1HNMR
HEXOBARBITAL(56-29-1)13CNMR
HEXOBARBITAL(56-29-1)IR1
HEXOBARBITAL(56-29-1)Raman
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