| Identification | Back Directory | [Name]
3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXY-ALPHA,ALPHA-DIMETHYLBENZENEPROPANAL | [CAS]
56189-68-5 | [Synonyms]
CGP 13501
3-(3',5'-DI-TERT-BUTYL-4'-HYDROXY)PHENYL-2,2-DIMETHYLPROPANAL
3,5-bis(1,1-Dimethylethyl)-4-hydroxy-α,α-dimethylbenzenepropanal
Benzenepropanal, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-α,α-dimethyl-
3,5-BIS(1,1-DIMETHYLETHYL)-4-HYDROXY-ALPHA,ALPHA-DIMETHYLBENZENEPROPANAL | [Molecular Formula]
C19H30O2 | [MDL Number]
MFCD04040029 | [MOL File]
56189-68-5.mol | [Molecular Weight]
290.44 |
| Hazard Information | Back Directory | [Uses]
CGP 13501 is a positive allosteric modulator at GABAB?receptors. | [Definition]
ChEBI: 3-(3,5-ditert-butyl-4-hydroxyphenyl)-2,2-dimethylpropanal is an alkylbenzene. | [Biological Activity]
Positive allosteric modulator of GABA B receptors, potentiating the effects of GABA at this receptor type. | [References]
[1]. urwyler s, mosbacher j, lingenhoehl k, et al. positive allosteric modulation of native and recombinant gamma-aminobutyric acid(b) receptors by 2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (cgp7930) and its aldehyde analog cgp13501. mol pharmacol, 2001, 60(5): 963-971.
[2]. rasheed n, ahmad a, al-sheeha m, et al. neuroprotective and anti-stress effect of a68930 in acute and chronic unpredictable stress model in rats. neurosci lett, 2011, 504(2): 151-155. |
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