ChemicalBook--->CAS DataBase List--->56290-94-9

56290-94-9

56290-94-9 Structure

56290-94-9 Structure
IdentificationBack Directory
[Name]

5-[2-[[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino]-1-hydroxyethyl]salicylamide
[CAS]

56290-94-9
[Synonyms]

RMI-81968
Medroxalol
5-[2-[4-(1,3-benzodioxol-5-yl)butan-2-ylamino]-1-hydroxyethyl]-2-hydroxybenzamide
5-[2-[[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino]-1-hydroxyethyl]salicylamide
5-[2-[[3-(1,3-Benzodioxol-5-yl)-1-methylpropyl]amino]-1-hydroxyethyl]-2-hydroxybenzamide
Benzamide, 5-[2-[[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino]-1-hydroxyethyl]-2-hydroxy-
[EINECS(EC#)]

260-099-3
[Molecular Formula]

C20H24N2O5
[MOL File]

56290-94-9.mol
[Molecular Weight]

372.42
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

soluble in No data available
[form ]

Solid
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

Antihypertensive.
[Uses]

Medroxalol is an antihypertensive agent that possesses both alpha and beta-adrenergic antagonistic properties. Medroxalol is used to treat mild and moderate hypertension.
[Definition]

ChEBI: Medroxalol is a member of salicylamides.
[in vivo]

Medroxalol (oral gavage; 12.5-50 mg/kg; once daily; 12 d) treatment shows antihypertensive activity in spontaneously hypertensive rats[1].

Animal Model:Male spontaneously hypertensive rats (SHR)[1]
Dosage:12.5, 25, or 50 mg/kg
Administration:Oral gavage; 12.5, 25, or 50 mg/kg; once daily; 12 days
Result:Produced a dose-related fall in blood pressure.
[storage]

Store at -20°C
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36894-69-6 66722-44-9 65-45-2 90274-24-1 39506-61-1

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