| Identification | Back Directory | [Name]
3,4-DIPHENYL-5H-FURAN-2-ONE | [CAS]
5635-16-5 | [Synonyms]
3,4-diphenyl-2H-furan-5-one
2(5H)-Furanone, 3,4-diphenyl-
3,4-Diphenyl-2,5-Dihydrofuran-2-One
3,4-Diphenyl-5H-furan-2-one, 10 mM in DMSO | [Molecular Formula]
C16H12O2 | [MDL Number]
MFCD00598262 | [MOL File]
5635-16-5.mol | [Molecular Weight]
236.27 |
| Hazard Information | Back Directory | [Uses]
3,4-Diphenyl-5H-furan-2-one is a natural compound isolated from the endophytic fungus Aspergillus flavipes AIL8 derived from the mangrove plant Acanthus ilicifolius. 3,4-Diphenyl-5H-furan-2-one is a derivative of 2,3-diphenyltetrahydrofuran (DPTF), which is a COX-2 inhibitor. 3,4-Diphenyl-5H-furan-2-one can be used as a lead compound for inflammation and pain[1][2]. | [References]
[1] Bai Z Q, et al. New phenyl derivatives from endophytic fungus Aspergillus flavipes AIL8 derived of mangrove plant Acanthus ilicifolius[J]. Fitoterapia, 2014, 95: 194-202. DOI:10.1016/j.fitote.2014.03.021
[2] Singh P, et al. 2, 3-Diphenyltetrahydrofurans (DPTF)-A new class of stereogenic diarylheterocycles as potential COX-2 inhibitors-Computational evaluation of COX-2-DPTF binding behaviour[J]. 2006. |
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