| Identification | Back Directory | [Name]
Flavomarein，2R-3',4',8-Trihydroxyflavanone-7-O-glucoside | [CAS]
56389-87-8 | [Synonyms]
2R-3',4',8-Trihydroxyflavanone-7-O-glucoside
Flavomarein，2R-3',4',8-Trihydroxyflavanone-7-O-glucoside
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-, (R)- (9CI) | [Molecular Formula]
C21H22O11 | [MOL File]
56389-87-8.mol | [Molecular Weight]
450.4 |
| Hazard Information | Back Directory | [Uses]
(2R)-Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. (2R)-Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities[1][2]. | [References]
[1] Nan-Nan Zhang, et al. Flavanomarein inhibits high glucose-stimulated epithelial-mesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase. Sci Rep. 2020 Jan 16;10(1):439. DOI:10.1038/s41598-019-57360-4
[2] Liang Le, et al. The protective effects of the native flavanone flavanomarein on neuronal cells damaged by 6-OHDA. Phytomedicine. 2019 Feb;53:193-204. DOI:10.1016/j.phymed.2018.09.005 |
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