ChemicalBook--->CAS DataBase List--->565452-98-4

565452-98-4

565452-98-4 Structure

565452-98-4 Structure
IdentificationBack Directory
[Name]

Vildagliptin Chloroacetyl Nitrile (R)-Isomer
[CAS]

565452-98-4
[Synonyms]

Vildagliptin Impurity 7
Vildagliptin impurities14
Vildagliptin?Chloroacetyl Nitrile (R)-Isomer
(R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
(R)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile
(2R)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile
2-Pyrrolidinecarbonitrile, 1-(2-chloroacetyl)-, (2R)-
2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-, (2R)- (9CI)
Vildagliptin Impurity 15/Vildagliptin Chloroacetyl Nitrile (R)-Isomer/(1S)-2-(2-chloroacetyl)cyclopentane-1-carbonitrile
[Molecular Formula]

C7H9ClN2O
[MDL Number]

MFCD11215489
[MOL File]

565452-98-4.mol
[Molecular Weight]

172.61
Chemical PropertiesBack Directory
[Melting point ]

64-67°C
[Boiling point ]

363.1±37.0 °C(Predicted)
[density ]

1.27±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

-4.65±0.40(Predicted)
[color ]

White to Pale Yellow
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H319
[Precautionary statements ]

P305+P351+P338
Hazard InformationBack Directory
[Uses]

(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, can be used in the synthesis of 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine, and Vildagliptin (C363780), which are potent, selective, and orally bioavailable dipeptidyl peptidase IV Inhibitor with Antihyperglycemic properties, that might be used for the treatment of type 2 diabetes.
[Uses]

(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, can be used in the synthesis of 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine, and Vildagliptin (C363780), which are potent, selective, and orally bioavailable dipeptidyl peptidase IV Inhibitor with Antihyperglycemic properties, that might be used for the treatment of type 2 diabetes.
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