ChemicalBook--->CAS DataBase List--->565460-15-3

565460-15-3

565460-15-3 Structure

565460-15-3 Structure
IdentificationBack Directory
[Name]

URB602
[CAS]

565460-15-3
[Synonyms]

URB602
N-[1,1'-Biphenyl]-3-yl-
URB602 ada@tuskwei.com whatsapp
cyclohexyl biphenyl-3-ylcarbaMate
Cyclohexyl [1,1'-biphenyl]-3-ylcarbaMate
Monoacylglycerol Lipase Inhibitor, URB602
Biphenyl-3-yl Carbamic Acid, Cyclohexyl Ester
[1,1’-Biphenyl]-3-yl-carbamic acid cyclohexyl ester
[Molecular Formula]

C19H21NO2
[MDL Number]

MFCD08457914
[MOL File]

565460-15-3.mol
[Molecular Weight]

295.38
Chemical PropertiesBack Directory
[Appearance]

Off-White Solid
[Melting point ]

122-123°C
[storage temp. ]

2-8°C
[solubility ]

DMSO: >10mg/mL
[form ]

powder
[color ]

white to off-white
Hazard InformationBack Directory
[Chemical Properties]

Off-White Solid
[Uses]

URB602 is a selective inhibitor of MGL, exhibiting an IC50 of 28 for the rat brain enzyme. It does not inhibit fatty acid amide hydrolase (FAAH) at concentrations up to 100 , or other lipid metabolizing enzymes such as diacylglycerol lipase or
[Uses]

URB602 is a selective inhibitor of MGL, exhibiting an IC50 of 28 μM for the rat brain enzyme. It does not inhibit fatty acid amide hydrolase (FAAH) at concentrations up to 100 μM, or other lipid metabolizing enzymes such as diacylglycerol lipase or cyclooxygenase-2.5 6 Inhibition of 2-AG hydrolysis is associated with enhanced stress-induced analgesia and may represent a novel drug target in pain and stress management.
Safety DataBack Directory
[WGK Germany ]

3
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