| Identification | Back Directory | [Name]
N-(2-FUROYL)GLYCINE | [CAS]
5657-19-2 | [Synonyms]
furoilglicina
furoylglycine
2-furoylglycine
furfuroylglycine
Pyromucuric acid
n-2-furoyl-glycin
AKOS BBS-00000709
N-(2-FUROYL)GLYCINE
N-(2-furoyl)glycinate
n-(2-furanylcarbonyl)-glycin
n-(2-furanylcarbonyl)glycine
N-(2-FUROYL)GLYCINE USP/EP/BP
Glycine, N-(2-furanylcarbonyl)-
2-(furan-2-carbonylamino)aceticaci
2-(2-furylcarbonylamino)acetic acid
2-(furan-2-carbonylamino)acetic acid | [Molecular Formula]
C7H7NO4 | [MDL Number]
MFCD00030606 | [MOL File]
5657-19-2.mol | [Molecular Weight]
169.13 |
| Chemical Properties | Back Directory | [Melting point ]
163-165 °C(lit.)
| [Boiling point ]
466.0±25.0 °C(Predicted) | [density ]
1.367±0.06 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
3.66±0.10(Predicted) | [color ]
White to Off-White | [biological source]
synthetic | [Water Solubility ]
>21.55 mg/mL in Water with ultrasonic; | [Stability:]
Hygroscopic | [Major Application]
peptide synthesis | [InChI]
1S/C7H7NO4/c9-6(10)4-8-7(11)5-2-1-3-12-5/h1-3H,4H2,(H,8,11)(H,9,10) | [InChIKey]
KSPQDMRTZZYQLM-UHFFFAOYSA-N | [SMILES]
OC(=O)CNC(=O)c1ccco1 |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36 | [WGK Germany ]
2
| [RTECS ]
MC0555300
| [HazardClass ]
IRRITANT | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Uses]
2-Furoylglycine is an intermediate used to prepare non-nucleoside inhibitors of HCV NS5b RNA polymerase. It is also used in the synthesis of benzimidazolylazabicyclooctylethylpiperidines as Ccr5 antagonists for the treatment of HIV infection. | [Definition]
ChEBI: N-(2-furoyl)glycine is a glycine derivative that is the carboxamide obtained by the formal condensation of the amino group of glycine with 2-furoic acid. It has a role as a human metabolite. It is a N-acylglycine and a member of furans. It is functionally related to a 2-furoic acid. It is a conjugate acid of a N-(2-furoyl)glycinate. | [IC 50]
Human Endogenous Metabolite; Microbial Metabolite |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|