| Identification | Back Directory | [Name]
6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride | [CAS]
56776-32-0 | [Synonyms]
StresaM
HOE-36801 hydrochloride
Etifoxine·hydrochloride
NSC 163501;ANTIBIOTIC AT-125;U 42126
2-EthylaMino-6-chloro-4-Methyl-4-phenyl-4H-3,1-benzoxazine Hydrochloride
6-Chloro-N-ethyl-4-Methyl-4-phenyl-4H-3,1-benzoxazin-2-aMine Hydrochloride
6-Chloro-2-(ethylamino)-4-methyl-4-phenyl-4H-3,1-benzoxazine hydrochloride
6-Chloro-2-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-aminehydrochloride
6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride | [EINECS(EC#)]
260-380-0 | [Molecular Formula]
C17H18Cl2N2O | [MDL Number]
MFCD18086857 | [MOL File]
56776-32-0.mol | [Molecular Weight]
337.244 |
| Hazard Information | Back Directory | [Chemical Properties]
Low Melting White Solid | [Uses]
Psychotropic agent with anxiolytic and anticonvulsant activity. | [Biochem/physiol Actions]
Etifoxine is an anxiolytic anticonvulsant, which promotes axonal regeneration. It binds to β2 and β3 subunits of the GABAA receptor complex, a different target site to benzodiazepines, and binds to the translocator protein (18 kDa) TSPO, formerly known as the peripheral or mitochondrial benzodiazepine receptor. TSPO carries cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step of steroidogenesis. Whereas, its anxiolytic effects involve GABAA receptors and TSPO, etifoxine′s neuroregenerative effects mainly involve TSPO. | [storage]
Store at +4°C |
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