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56821-03-5

56821-03-5 Structure

56821-03-5 Structure
IdentificationBack Directory
[Name]

10H-Phenoxazine, 2-chloro-
[CAS]

56821-03-5
[Synonyms]

2-Chlorophenoxazine
10H-Phenoxazine, 2-chloro-
[Molecular Formula]

C12 H8 Cl N O
[MOL File]

56821-03-5.mol
[Molecular Weight]

217.65
Chemical PropertiesBack Directory
[Melting point ]

143-146 °C
[Boiling point ]

344.8±41.0 °C(Predicted)
[density ]

1.318±0.06 g/cm3(Predicted)
[pka]

0.77±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

2-Chlorophenoxazine is a Akt inhibitor with an IC50 value of 2-5 μM for in vitro. 2-Chlorophenoxazine can induce apoptosis. 2-Chlorophenoxazine can be used for cancer diseases research[1].
[References]

[1] Thimmaiah KN, et al. Identification of N10-substituted phenoxazines as potent and specific inhibitors of Akt signaling. J Biol Chem. 2005 Sep 9;280(36):31924-35 DOI:10.1074/jbc.M507057200
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