| Identification | Back Directory | [Name]
XANTHOHUMOL | [CAS]
569-83-5 | [Synonyms]
Xanthohumol1
1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)- 2-propen-1-one
2-Propen-1-one, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)- | [Molecular Formula]
C21H22O5 | [MDL Number]
MFCD00210576 | [MOL File]
569-83-5.mol | [Molecular Weight]
354.4 |
| Chemical Properties | Back Directory | [Boiling point ]
576.5±50.0 °C(Predicted) | [density ]
1.244±0.06 g/cm3(Predicted) | [solubility ]
Soluble to 100 mM in DMSO and to 100 mM in ethanol | [form ]
powder | [pka]
7.47±0.45(Predicted) | [color ]
Yellow |
| Hazard Information | Back Directory | [Uses]
(E/Z)-Xanthohumol is a flavonoid isolated from hopfen[1]. | [Definition]
ChEBI: Xanthohumol is a member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2' and 4', a methoxy group at position 6' and a prenyl group at position 3'. Isolated from Humulus lupulus, it induces apoptosis in human malignant glioblastoma cells. It has a role as a metabolite, an apoptosis inducer, an antineoplastic agent, an antiviral agent, an EC 2.3.1.20 (diacylglycerol O-acyltransferase) inhibitor and an anti-HIV-1 agent. It is a member of chalcones, a polyphenol and an aromatic ether. It is a conjugate acid of a xanthohumol(1-). | [References]
[1] Rudolf H?nsel, et al. Desmethylxanthohumol: Isolierung aus Hopfen und Cyclisierung zu Flavanonen. Arch. Der Pharm.1988, 321, 1. |
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| Company Name: |
Shaanxi Dideu Medichem Co. Ltd
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| Telephone: |
+86-29-87569266 +86-17392581500 |
| Website: |
https://www.chemicalbook.com/manufacturer/shaanxi-dideu-medichem-220/ |
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