ChemicalBook--->CAS DataBase List--->57262-94-9

57262-94-9

57262-94-9 Structure

57262-94-9 Structure
IdentificationBack Directory
[Name]

Setiptiline
[CAS]

57262-94-9
[Synonyms]

Tecipul
Org-8282
Teciptiline
Setiptiline
Teciptilline
Setiptiline USP/EP/BP
Setiptiline(Teciptilline)
TECIPTILLINE;ORG 8282;ORG8282;ORG-8282
2,3,4,9-Tetmhydro-2-methyl-1H-dibenzo[3,4:6,7]cyelohepta[1,2-c]pyridine
2,3,4,9-tetrahydro-2-methyl-1H-dibenzo[3,4:6,7]cyclohepta[1,2-c]pyridine
1H-Dibenzo[3,4:6,7]cyclohepta[1,2-c]pyridine, 2,3,4,9-tetrahydro-2-methyl-
1H-Dibenzo[3,4:6,7]cyclohepta[1,2-c]pyridine,2,3,4,9-tetrahydro-2-methyl-Org 8282
[EINECS(EC#)]

260-653-4
[Molecular Formula]

C19H19N
[MDL Number]

MFCD00868385
[MOL File]

57262-94-9.mol
[Molecular Weight]

261.366
Chemical PropertiesBack Directory
[Melting point ]

>120°C (dec.)
[Boiling point ]

421.7±34.0 °C(Predicted)
[density ]

1.15
[storage temp. ]

Sealed in dry,Store in freezer, under -20°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

8.34±0.20(Predicted)
[color ]

White to Light Yellow
Raw materials And Preparation ProductsBack Directory
[Raw materials]

polyphosphoric acid
Hazard InformationBack Directory
[Description]

Setiptiline is a mianserin analog reportedly useful in the treatment of depression with a favorable side-effect profile. It is a potent antagonist of alpha-receptors, with greater affinity at alpha, than alpha, sites, as well as an inhibitor of central serotonin receptors.
[Chemical Properties]

Flaky crystals. Soluble in ethyl acetate, benzene, or chloroform, insoluble in ethanol. Melting point 138.5-139.5°C.
Setiptiline Maleate: C19H19N·C4H4O4. [57262-95-0]. White to slightly yellowish-white crystalline powder, odorless, bitter taste. Freely soluble in chloroform, soluble in methanol, slightly soluble in ethanol, slightly soluble in water. Melting point 153-158°C.
[Originator]

Organon (Netherlands)
[Uses]

Setiptiline is a tetracyclic antidepressant. Setiptiline acts as a noradrenergic and specific serotonergic antidepressant (NaSSA).
[Definition]

ChEBI: Setiptiline is a tetracyclic antidepressant that is 2,3,4,9-tetrahydro-1H-dibenzo[3,4:6,7]cyclohepta[1,2-c]pyridine carrying a methyl group at position 2. Its maleate salt is used for the treatment of depression in Japan. It has a role as an alpha-adrenergic antagonist and a serotonergic antagonist. It is a tetracyclic antidepressant and a tertiary amino compound. It is a conjugate base of a setiptiline(1+).
[Brand name]

Tecipul
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