Identification | Back Directory | [Name]
(E)-methyl 3-(3-(N-(4-styrylbenzyl)cyclohexanecarboxamido)phenyl)acrylate | [CAS]
574013-68-6 | [Synonyms]
FEXARENE Methyl 3-(3-(N-(4-(styryl)benzyl)cyclohexanecarboxamido)phenyl)acrylate (E)-methyl 3-(3-(N-(4-styrylbenzyl)cyclohexanecarboxamido)phenyl)acrylate 2-Propenoic acid, 3-[3-[(cyclohexylcarbonyl)[[4-(2-phenylethenyl)phenyl]methyl]amino]phenyl]-, methyl ester | [Molecular Formula]
C32H33NO3 | [MDL Number]
MFCD29035145 | [MOL File]
574013-68-6.mol | [Molecular Weight]
479.61 |
Hazard Information | Back Directory | [Description]
Fexarene is a non-steroidal FXR agonist. | [Uses]
Fexarene is a potent and selective nonsteroidal Farnesoid X Receptor (FXR) agonist with an EC50 of 36 nM. Fexarene can be used in studies of cholesterol and bile acid metabolism[1]. | [References]
[1] Nicolaou KC, et al. Discovery and optimization of non-steroidal FXR agonists from natural product-like libraries. Org Biomol Chem. 2003 Mar 21;1(6):908-20. PMID:12929628 |
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Biorbyt Ltd.
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A.J Chemicals
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