| Identification | Back Directory | [Name]
sodium 2-(3-benzoylphenyl)propionate | [CAS]
57495-14-4 | [Synonyms]
19583-RP-Na
19583-RP sodium
Ketoprofen sodium
Sodium ketoprofen
KETOPROFEN SODIUM SALT
sodium,2-(3-benzoylphenyl)propanoate
sodium 2-(3-benzoylphenyl)propionate
3-Benzoyl-α-methylbenzeneacetic acid sodium salt | [EINECS(EC#)]
260-770-0 | [Molecular Formula]
C16H13NaO3 | [MDL Number]
MFCD01733104 | [MOL File]
57495-14-4.mol | [Molecular Weight]
276.262 |
| Hazard Information | Back Directory | [Uses]
Ketoprofen (RP-19583) sodium is a non-steroidal anti-inflammatory agent. Ketoprofen sodium can inhibit the activity of Cyclooxygenase with IC50 values of 2 nM (COX-1) and 26 nM (COX-2). Ketoprofen is potential in the research of inflammation, immunology, and metabolic disease such as obesity[1][2][3]. | [References]
[1] Palomer A, et al. Structure-based design of cyclooxygenase-2 selectivity into ketoprofen. Bioorg Med Chem Lett. 2002 Feb 25;12(4):533-7. DOI:10.1016/s0960-894x(01)00800-9
[2] NamHyeon Kang Ketoprofen alleviates diet-induced obesity and promotes white fat browning in mice via the activation of COX-2 through mTORC1-p38 signaling pathway. Pflugers Arch. 2020 May;472(5):583-596. DOI:10.1097/j.pain.0000000000000171
[3] Denisa Dan, et al. Ketoprofen affects the mammary immune response in dairy cows in vivo and in vitro. J Dairy Sci. 2018 Dec;101(12):11321-11329. DOI:10.3168/jds.2018-15034 |
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Bide Pharmatech Ltd.
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400-1647117 13681763483 |
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https://www.bidepharm.com/ |
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TargetMol
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www.targetmol.cn/ |
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