| Identification | Back Directory | [Name]
(±)-5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene bisisobutyrate hydrochloride | [CAS]
57576-17-7 | [Synonyms]
dl-Ibuterol hydrochloride
(±)-5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene bisisobutyrate hydrochloride | [EINECS(EC#)]
260-823-8 | [Molecular Formula]
C20H31NO5.ClH | [MOL File]
57576-17-7.mol | [Molecular Weight]
401.925 |
| Hazard Information | Back Directory | [Uses]
Ibuterol (KWD 2058) hydrochloride, a diester of Terbutaline (HY-B0802A), is an orally active, selective and effective β-stimulating agent with lipophilic activities. Ibuterol hydrochloride is also an orally active ocular hypotensive agent. Ibuterol hydrochloride relieves bronchial obstruction in asthma without causing circulatory effects. Ibuterol hydrochloride is proming for rasearch of intraocular hypertension, asthma and bronchitis[1][2][3]. | [References]
[1] Arner B, et al. Comparison between ibuterol hydrochloride and terbutaline in asthma. Br Med J. 1976 Jan 10;1(6001):72-4. DOI:10.1136/bmj.1.6001.72
[2] Phipps TL, et al. Effects of ibuterol, a beta-2 adrenergic prodrug, on intraocular pressure. J Ocul Pharmacol. 1986 Summer;2(3):225-37. DOI:10.1089/jop.1986.2.225
[3] Larsson S, et al. Comparison of intravenous ibuterol (KWD 2058), a new bronchodilator, and terbutaline. Eur J Clin Pharmacol. 1977 Jul 19;11(6):429-33. DOI:10.1007/BF00562933 |
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