| Identification | Back Directory | [Name]
6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole | [CAS]
577696-37-8 | [Synonyms]
CDNG1
Cardionogen 1
Cardionogen-1/vuc230
6-Cyclohexyl-3-(2-furanyl)-1,2,4-triazolo[3,4-b][1,3,4]thiadiazole
6-Cyclohexyl-3-furan-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
1,2,4-Triazolo[3,4-b][1,3,4]thiadiazole, 6-cyclohexyl-3-(2-furanyl)- | [Molecular Formula]
C13H14N4OS | [MDL Number]
MFCD04027630 | [MOL File]
577696-37-8.mol | [Molecular Weight]
274.34 |
| Hazard Information | Back Directory | [Uses]
A small molecule promoter affecting cardiomyocyte generation through modulation of the wnt signaling pathway. | [Definition]
ChEBI: Cardionogen-1 is a triazolothiadiazole that is [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole which is substituted at positions 3 and 6 by 2-furyl and cyclohexyl groups, respectively. A cardiomyocyte promoter and an inhibitor of Wnt/beta-catenin dependent transcriptional activity, it induces cardiac cell formation in murine stem cells and zebrafish embryos, expanding cardiac progenitor cells. A biphasic modulator of cardiogenesis, it can act as either a promotor or inhibitor of heart formation, depending on the stage of treatment. It has a role as a Wnt signalling inhibitor. It is a triazolothiadiazole and a member of furans. |
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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