| Identification | Back Directory | [Name]
2-hydroxy-5-[[(p-tolyl)sulphonyl]oxy]benzenesulphonic acid, compound with piperazine (1:1) | [CAS]
57775-27-6 | [Synonyms]
A585
A 585
A-585
Mimedran
Piperazine salt
piperazine-sultosylate
Sultosilic acid, piperazine salt
2-hydroxy-5-[[(p-tolyl)sulphonyl]oxy]benzenesulphonic acid, compound with piperazine (1:1) | [EINECS(EC#)]
260-944-6 | [Molecular Formula]
C17H22N2O7S2 | [MDL Number]
MFCD01658053 | [MOL File]
57775-27-6.mol | [Molecular Weight]
430.496 |
| Hazard Information | Back Directory | [Uses]
Sultosilic acid piperazine salt (Piperazine sultosylate; A-585) is a lipid-lowering agent. Sultosilic acid piperazine salt modifies the blood lipids levels, reduces platelet adhesiveness without promoting peroxisomal activity of hepatocytes or producing other adverse side-effects[1]. | [References]
[1] Vinazzer H, et al., Double-blind cross-over study of the effect of sultosilic acid piperazine salt (A-585) and bezafibrate in primary hyperlipoproteinemia. Atherosclerosis. 1983 Nov;49(2):109-18. DOI:10.1016/0021-9150(83)90188-0 |
| Safety Data | Back Directory | [Toxicity]
LD50 i.p. in beagles, male rats, female rats: 605, 833.6, 1272 mg/kg; orally in rats: >11 g/kg (Rodriguez) |
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