ChemicalBook--->CAS DataBase List--->5778-80-3

5778-80-3

5778-80-3 Structure

5778-80-3 Structure
IdentificationBack Directory
[Name]

TA-03
[CAS]

5778-80-3
[Synonyms]

TA-03
7-Meota
TA 03,TA03
7-Methoxytacrine
7-methoxy-1,2,3,4-tetrahydroacridin-9-amine
9-Acridinamine, 1,2,3,4-tetrahydro-7-methoxy-
[Molecular Formula]

C14H16N2O
[MDL Number]

MFCD01237613
[MOL File]

5778-80-3.mol
[Molecular Weight]

228.29
Chemical PropertiesBack Directory
[Melting point ]

212-213 °C
[Boiling point ]

443.1±45.0 °C(Predicted)
[density ]

1.202±0.06 g/cm3(Predicted)
[pka]

9.70±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

7-Methoxytacrine (7-MEOTA) is an inhibitor of human acetylcholinesterase (hAChE) with an IC50 value of 10 μM, and can be used for the research of Alzheimer's disease (AD)[1].
[IC 50]

hAChE: 10.5 μM (IC50); hBCHE: 21 μM (IC50)
[References]

[1] Spilovska K, et al. 7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer's disease treatment--synthesis, biological evaluation and molecular modeling studies. Molecules. 2013;18(2):2397-2418. Published 2013 Feb 20. DOI:10.3390/molecules18022397
Spectrum DetailBack Directory
[Spectrum Detail]

TA-03(5778-80-3)1HNMR
5778-80-3 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354 , +17819995354
Website: https://www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Website: https://www.targetmol.com/
Company Name: Amatek Scientific Co. Ltd.  
Tel: 0512-56316828
Website: http://www.amateksci.com
Company Name: Shanghai Haohong Pharmaceutical Co., Ltd.  
Tel: 400-8210725 4008210725
Website: https://www.leyan.com/
Company Name: Block Chemical Technology (Shanghai) Co., LTD  
Tel: 021-20432219 13918097649
Website: www.acblock-lab.com
Company Name: cjbscvictory  
Tel: 13348960310 13348960310;
Website: https://www.weikeqi-biotech.com/
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Website: https://www.targetmol.cn/
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Beijing Boorsen Biotechnology Co., Ltd  
Tel: 400-901-9800 18611424007
Website: www.bioss.com.cn/
Company Name: Sangon Biotech (Shanghai) Co.,Ltd.  
Tel: 400-821-026
Website: www.sangon.com
Company Name: Biosynth Biological Technology (Suzhou) Co Ltd  
Tel: 51288865780
Website: www.biosynth.com
Company Name: Shanghai Amole Biotechnology Co., Ltd.  
Tel: 18916360931 18916360931
Website: www.amole.com.cn/
Company Name: Absin Bioscience Inc.  
Tel: 021-38015121-8802
Website: http://www.absin.cn
Company Name: Proteintech China  
Tel: 027-87531629
Website: http://www.ptgcn.com
Company Name: Guangzhou New Century Technology Co., Ltd.  
Tel: 020-13113998854 13113998854
Website: www.chemicalbook.com/showsupplierproductslist32626/0_en.htm
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
Tel: 025-85560043 15850508050
Website: http://www.synzest.com
Tags:5778-80-3 Related Product Information
321-64-2